C
Carla Sollaino
Researcher at University of Cagliari
Publications - 11
Citations - 822
Carla Sollaino is an academic researcher from University of Cagliari. The author has contributed to research in topics: Thalassemia & Glucose-6-phosphate dehydrogenase. The author has an hindex of 7, co-authored 11 publications receiving 757 citations.
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Journal ArticleDOI
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia
Manuela Uda,Renzo Galanello,Serena Sanna,Guillaume Lettre,Guillaume Lettre,Vijay G. Sankaran,Wei-Min Chen,Gianluca Usala,Fabio Busonero,Andrea Maschio,Giuseppe Albai,Maria Grazia Piras,Natascia Sestu,Sandra Lai,Mariano Dei,Antonella Mulas,Laura Crisponi,Silvia Naitza,Isadora Asunis,Manila Deiana,Ramaiah Nagaraja,Lucia Perseu,Stefania Satta,Maria Dolores Cipollina,Carla Sollaino,Paolo Moi,Joel N. Hirschhorn,Joel N. Hirschhorn,Stuart H. Orkin,G. Abecasis,David Schlessinger,Antonio Cao +31 more
TL;DR: It is indicated that BCL11A variants, by modulating HbF levels, act as an important ameliorating factor of the β-thalassemia phenotype, and it is likely they could helpAmeliorate other hemoglobin disorders.
Journal ArticleDOI
Genotype of subjects with borderline hemoglobin A2 levels: Implication for, β‐thalassemia carrier screening
Renzo Galanello,Susanna Barella,A. Ideo,D. Gasperini,C. Rosatelli,L. Paderi,E. Paglietti,Carla Sollaino,L. Perseu,D. Loi,Antonio Cao +10 more
TL;DR: It may be concluded that subjects with borderline HbA2, particularly when they marry a typical β‐thal carrier, should be extensively investigated in order not to miss heterozygousβ‐thalassemia.
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Molecular Characterization of β-Thalassemia in Pakistan
TL;DR: Thalassemia patients with triplicated α genes were homozygous for either the β+ or the β0 genotype, and two rare alleles in the Pakistani population, −α4.2 and αααanti 3.7, were identified in these patients.
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α-thalassemia carrier identification by DNA analysis in the screening for thalassemia
Renzo Galanello,Carla Sollaino,E. Paglietti,Susanna Barella,C Perra,Ilaria Doneddu,Maria G. Pirroni,L Maccioni,Antonio Cao +8 more
TL;DR: The identification of the α‐thalassemia carrier state may be fast and accurate by PCR‐based method, avoiding other cumbersome and expensive methods such as globin chain synthesis and Southern blot analysis.
Journal ArticleDOI
New analytical tools and epidemiological data for the identification of HbA2 borderline subjects in the screening for beta-thalassemia.
Andrea Mosca,Renata Paleari,Renzo Galanello,Carla Sollaino,Lucia Perseu,Franca Rosa Demartis,Cristina Passarello,Antonino Giambona,Aurelio Maggio +8 more
TL;DR: A retrospective investigation in two centres with high prevalence of beta-thalassemia concluded that the occurrence of HbA(2) borderline phenotypes is not a rare event and the development of an international reference measurement system based on quantitative peptide mapping has been recently started.