C
Carlos F. Sánchez-Ferrer
Researcher at Autonomous University of Madrid
Publications - 108
Citations - 4146
Carlos F. Sánchez-Ferrer is an academic researcher from Autonomous University of Madrid. The author has contributed to research in topics: Endothelium & Vascular smooth muscle. The author has an hindex of 33, co-authored 101 publications receiving 3662 citations. Previous affiliations of Carlos F. Sánchez-Ferrer include Hospital Universitario La Paz.
Papers
More filters
Journal ArticleDOI
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
Evi Kostenis,Graeme Milligan,Arthur Christopoulos,Carlos F. Sánchez-Ferrer,Silvia Heringer-Walther,Patrick M. Sexton,Florian Gembardt,Elaine Kellett,Lene Martini,Patrick Vanderheyden,Heinz-Peter Schultheiss,Thomas Walther +11 more
TL;DR: It is demonstrated that Mas can hetero-oligomerize with the AT1 receptor and by so doing inhibit the actions of angiotensin II, a novel demonstration that a G-protein–coupled receptor acts as a physiological antagonist of a previously characterized receptor.
Journal ArticleDOI
Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation.
Leocadio Rodríguez-Mañas,Mariam El-Assar,Susana Vallejo,Pedro López-Dóriga,Joaquin Solís,Roberto Petidier,Manuel Montes,Julián Nevado,Marta Castro,Carmen Gomez-Guerrero,Concepción Peiró,Carlos F. Sánchez-Ferrer +11 more
TL;DR: It is concluded that the age‐dependent endothelial dysfunction in human vessels is due to the combined effect of oxidative stress and vascular wall inflammation.
Journal ArticleDOI
Mechanisms involved in the aging-induced vascular dysfunction.
Mariam El Assar,Javier C. Angulo,Susana Vallejo,Concepción Peiró,Carlos F. Sánchez-Ferrer,Leocadio Rodríguez-Mañas +5 more
TL;DR: Prevention or reversion of those mechanisms leading to endothelial dysfunction through life style modifications or pharmacological interventions could markedly improve cardiovascular health in older people.
Journal ArticleDOI
Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity
Tania Romacho,Veronica Azcutia,M. Vázquez-Bella,Nuria Matesanz,Elena Cercas,Julián Nevado,R. Carraro,Leocadio Rodríguez-Mañas,Carlos F. Sánchez-Ferrer,Concepción Peiró +9 more
TL;DR: Through its intrinsic NAMPT activity, ePBEF/NAMPT/visfatin appears to be a direct contributor to vascular inflammation, a key feature of atherothrombotic diseases linked to metabolic disorders.
Journal ArticleDOI
Visfatin/Nampt: an adipokine with cardiovascular impact
TL;DR: Visfatin/Nampt effects on cytokine and chemokine secretion, macrophage survival, leukocyte recruitment by endothelial cells, vascular smooth muscle inflammation and plaque destabilization make of this adipokine an active factor in the development and progression of atherosclerosis.