C
Carmine Gentile
Researcher at University of Technology, Sydney
Publications - 47
Citations - 2040
Carmine Gentile is an academic researcher from University of Technology, Sydney. The author has contributed to research in topics: Medicine & Stem cell. The author has an hindex of 15, co-authored 38 publications receiving 1654 citations. Previous affiliations of Carmine Gentile include Sewanee: The University of the South & Harvard University.
Papers
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Journal ArticleDOI
Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin-angiotensin-aldosterone system (RAAS) dysregulation.
Robin Augustine,Maria Cristina Fernandes Salles Altman,Abhilash S,Ajisha Nayeem,Shaheen Abdul Salam,Priya Augustine,Pan Dan,Pablo Maureira,Fatima Mraiche,Carmine Gentile,Carmine Gentile,Carmine Gentile,Philip M. Hansbro,Lana McClements,Anwarul Hasan +14 more
TL;DR: In this article, the authors reviewed the current knowledge and outline the gaps related to the relationship between CVD and COVID-19 with a focus on the renin-angiotensin-aldosterone system (RAAS).
Journal ArticleDOI
Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells.
Robin Augustine,Pan Dan,Anwarul Hasan,Israa Magdi Nassef Khalaf,Parvathy Prasad,Kajal Ghosal,Carmine Gentile,Lana McClements,Pablo Maureira +8 more
TL;DR: A detailed overview of the recent advances in microengineering of autologous stem cell-based tissue engineering platforms for the repair of damaged cardiac tissue is provided in this paper, where a particular emphasis is given to the roles played by the extracellular matrix (ECM) in regulating the physiological response of stem cells within cardiac tissue engineering platform.
Journal ArticleDOI
Towards engineering heart tissues from bioprinted cardiac spheroids.
Liudmila Polonchuk,Lydia Surija,Min Ho Lee,Poonam Sharma,Clara Liu Chung Ming,Florian Richter,Eitan Ben-Sefer,Maryam Alsadat Rad,Hadi Mahmodi Sheikh Sarmast,Wafa Al Shamery,Hien A. Tran,Laura Vettori,Fabian Haeusermann,Elysse C. Filipe,Jelena Rnjak-Kovacina,Thomas R. Cox,Joanne L. Tipper,Irina V. Kabakova,Carmine Gentile +18 more
TL;DR: In this article, the use of cardiac spheroids (CSs) to biofabricate novel and advanced physiological cardiac models for in vitro testing was explored, where CSs were created from human myocytes, fibroblasts and endothelial cells, mixed within optimal alginate/gelatin (Al/Ge) hydrogels and then bioprinted on a microelectrode plate for drug testing.
Book ChapterDOI
Stem Cell-Derived Cardiac Spheroids as 3D In Vitro Models of the Human Heart Microenvironment
Madeline Campbell,Mamta Chabria,Gemma A. Figtree,Liudmila Polonchuk,Carmine Gentile,Carmine Gentile,Carmine Gentile +6 more
TL;DR: Three-dimensional vascularized cardiac spheroids offer a promising platform to study cardiac physiology, disease, and pharmacology, as well as bioengineering constructs to regenerate heart tissue.
Journal ArticleDOI
Printability, Durability, Contractility and Vascular Network Formation in 3D Bioprinted Cardiac Endothelial Cells Using Alginate-Gelatin Hydrogels.
Christopher D Roche,Poonam Sharma,Poonam Sharma,Poonam Sharma,Anthony W. Ashton,Christopher J. Jackson,Meilang Xue,Carmine Gentile,Carmine Gentile +8 more
TL;DR: In this paper, the authors evaluated 3D-bioprinted double-layer patches using alginate/gelatine hydrogels and three extrusion bioprinters (REGEMAT3D, INVIVO, BIO X).