C
Carole Nicco
Researcher at French Institute of Health and Medical Research
Publications - 112
Citations - 5514
Carole Nicco is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Fibrosis & Reactive oxygen species. The author has an hindex of 34, co-authored 100 publications receiving 4578 citations. Previous affiliations of Carole Nicco include Paris Descartes University & Université du Québec.
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Journal ArticleDOI
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming
Elodie Segura,Carole Nicco,Carole Nicco,Bérangère Lombard,Bérangère Lombard,Philippe Veron,Philippe Veron,Graça Raposo,Graça Raposo,Frédéric Batteux,Frédéric Batteux,Sebastian Amigorena,Sebastian Amigorena,Clotilde Théry,Clotilde Théry +14 more
TL;DR: It is shown that exosomes secreted by lipopolysaccharide (LPS)-treated mature DCs are 50- to 100-fold more potent to induce antigen-specific T-cell activation in vitro than exosome from immature DCs.
Journal Article
Controlling Tumor Growth by Modulating Endogenous Production of Reactive Oxygen Species
Alexis Laurent,Carole Nicco,Christiane Chéreau,Claire Goulvestre,Jérôme Alexandre,Arnaud Alves,Eva Lévy,François Goldwasser,Yves Panis,Olivier Soubrane,Bernard Weill,Frédéric Batteux +11 more
TL;DR: In conclusion, antioxidant molecules may have opposite effects on tumor growth as SOD mimics can act in synergy with cytotoxic drugs to treat colon and liver cancers and reactive oxygen species can promote normal cellular proliferation and carcinogenesis.
Journal ArticleDOI
Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo.
Jérôme Alexandre,Frédéric Batteux,Carole Nicco,Christiane Chéreau,Alexis Laurent,Loïc Guillevin,Bernard Weill,François Goldwasser +7 more
TL;DR: The accumulation of H2O2 is an early and crucial step for paclitaxel‐induced cancer cell death before the commitment of the cells into apoptosis, suggesting that ROS participate in vitro and in vivo to pac litaxel cytotoxicity.
Journal ArticleDOI
Reactive Oxygen Species Controls Endometriosis Progression
Charlotte Ngo,Christiane Chéreau,Carole Nicco,Bernard Weill,Charles Chapron,Frédéric Batteux +5 more
TL;DR: The murine model shows that antioxidant molecules could be used as safe and efficient treatments for endometriosis and abrogated by the antioxidant molecule N-acetyl-cysteine both in vitro and in a mouse model of endometRIosis.
Journal ArticleDOI
Platelet CD154 Potentiates Interferon-α Secretion by Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus
Pierre Duffau,Julien Seneschal,Carole Nicco,Christophe Richez,Estibaliz Lazaro,Isabelle Douchet,Isabelle Douchet,Cécile Bordes,Jean-François Viallard,Claire Goulvestre,Jean-Luc Pellegrin,Bernard Weil,Jean-François Moreau,Frédéric Batteux,Patrick Blanco +14 more
TL;DR: In this article, platelet activation correlated with severity of the disease and activated platelets formed aggregates with antigen-presenting cells, including monocytes and plasmacytoid dendritic cells.