Carolina De La Guardia

TL;DR: The synthesis and antiviral activity evaluation of two compounds based on the quinoline scaffold, which has shown potential for the development of molecules with various biological activities, showed dose-dependent inhibition of dengue virus serotype 2 in the low and sub micromolar range.

TL;DR: An overview of the targets and progress that has been made in the quest for dengue virus entry inhibitors is provided, with a focus on the initial step in the infection.

TL;DR: Results of this study demonstrate that AFLP polymorphisms can be informative for genetic characterization in Leishmania parasites, at both intra and inter-specific levels.

TL;DR: Blind docking simulations were done to investigate the possible mode of binding, showing that all peptides appear to bind domain III of the protein and may be mostly stabilized by hydrophobic interactions.

TL;DR: In this paper, a lateral flow assay was used to identify specific IgM and IgG antibodies against SARS-CoV-2 and reported the seroprevalence estimates of these antibodies among health care workers and healthy volunteer blood donors in Panama.