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Caroline Colijn
Researcher at Simon Fraser University
Publications - 185
Citations - 6389
Caroline Colijn is an academic researcher from Simon Fraser University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 36, co-authored 162 publications receiving 4981 citations. Previous affiliations of Caroline Colijn include University of Waterloo & University of Bristol.
Papers
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Journal ArticleDOI
Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production.
Caroline Colijn,Caroline Colijn,Caroline Colijn,Aaron Brandes,Jeremy Zucker,Desmond S. Lun,Desmond S. Lun,Brian Weiner,Maha R. Farhat,Tan-Yun Cheng,D. Branch Moody,Megan Murray,James E. Galagan,James E. Galagan +13 more
TL;DR: E-Flux as mentioned in this paper extends the technique of Flux Balance Analysis by modeling maximum flux constraints as a function of measured gene expression, which can predict changes in metabolic flux capacity.
Journal ArticleDOI
Effects of smoking and solid-fuel use on COPD, lung cancer, and tuberculosis in China: a time-based, multiple risk factor, modelling study
TL;DR: Reducing smoking and solid-fuel use can substantially lower predictions of COPD and lung cancer burden and would contribute to effective tuberculosis control in China.
Journal ArticleDOI
A mathematical model of hematopoiesis--I. Periodic chronic myelogenous leukemia.
TL;DR: Several previous mathematical models of HSC dynamics, and models for the regulation of neutrophils, platelets and erythrocytes into a comprehensive model for theregulation of the hematopoietic system are synthesized.
Journal ArticleDOI
Evidence for transmission of COVID-19 prior to symptom onset.
Lauren C. Tindale,Jessica E. Stockdale,Michelle Coombe,Emma S Garlock,Wing Yin Lau,Manu Saraswat,Louxin Zhang,Dongxuan Chen,Jacco Wallinga,Caroline Colijn +9 more
TL;DR: The serial intervals are shorter than incubation periods, suggesting that pre-symptomatic transmission may occur in a large proportion of transmission events, and it is vital that even individuals who appear healthy abide by public health measures to control COVID-19.
Posted ContentDOI
Transmission interval estimates suggest pre-symptomatic spread of COVID-19
Lauren C. Tindale,Michelle Coombe,Jessica E. Stockdale,Emma S Garlock,Wing Yin Lau,Manu Saraswat,Yen-Hsiang Brian Lee,Louxin Zhang,Dongxuan Chen,Jacco Wallinga,Caroline Colijn +10 more
TL;DR: Estimated serial intervals are shorter than incubation periods in both Singapore and Tianjin, suggesting that pre-symptomatic transmission is occurring and that half of all secondary infections should be prevented to control spread.