C
Carolyn E. Mountford
Researcher at Translational Research Institute
Publications - 171
Citations - 5812
Carolyn E. Mountford is an academic researcher from Translational Research Institute. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & In vivo magnetic resonance spectroscopy. The author has an hindex of 44, co-authored 168 publications receiving 5406 citations. Previous affiliations of Carolyn E. Mountford include National Research Council & University of Sydney.
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A proteolipid in cancer cells is the origin of their high-resolution NMR spectrum
TL;DR: In this article, the spectrum of a proteolipid complex, isolated from the serum of patients with malignant diseases, is directly comparable with that obtained from intact cancer cells and solid tumours.
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Modulation of MR-visible mobile lipid levels by cell culture conditions and correlations with chemotactic response
Edward J. Delikatny,Catherine M. Lander,Thomas M. Jeitner,Rebecca L. Hancock,Carolyn E. Mountford +4 more
TL;DR: In this article, a transformed murine fibroblast cell line has been used to assess which criteria govern the appearance of a lipid pool that is mobile on the MR time scale, and the authors report that attenuation of cellular proliferation by confluence or low pH caused significant increases in MR-visible lipid and that the lipid signal could be amplified at high density by the removal of serum.
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Determination of grade and receptor status from the primary breast lesion by magnetic resonance spectroscopy.
Cynthia L. Lean,Sinead Doran,Ray L. Somorjai,Peter Malycha,David Clarke,Uwe Himmelreich,Roger Bourne,Brion Dolenko,Alexander E. Nikulin,Carolyn E. Mountford +9 more
TL;DR: Magnetic resonance spectra from fine needle aspiration biopsies from primary breast lesions were analysed using a pattern recognition method, Statistical Classification Strategy, to assess tumor grade and oestrogen receptor (ER) and progesterone receptor (PgR) status.
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Lipid and Metabolite Deregulation in the Breast Tissue of Women Carrying BRCA1 and BRCA2 Genetic Mutations
Saadallah Ramadan,Jameen Arm,Judith Silcock,Gorane Santamaria,Jessica Buck,Michele Roy,Kin Men Leong,Peter Lau,David E. Clark,Peter Malycha,Carolyn E. Mountford +10 more
TL;DR: Localized COSY recorded significant changes in women with BRCA1 and BRCa2 gene mutations when compared with control subjects, and if these changes are ultimately proven to be a premalignant stage, this method may prove useful in screening.
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Fucose in 1H COSY spectra of plasma membrane fragments shed from human malignant colorectal cells.
TL;DR: The methyl‐methine cross peak of bound fucose has been assigned in the COSY spectrum of plasma membrane shed from human malignant colorectal cells and Lactate anion, which was not perturbed by the hydrolysis, was used as an internal standard.