C
Carsten Lambert
Researcher at University of Mainz
Publications - 20
Citations - 1345
Carsten Lambert is an academic researcher from University of Mainz. The author has contributed to research in topics: Endoplasmic reticulum & Hepatitis B virus. The author has an hindex of 17, co-authored 20 publications receiving 1265 citations.
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Journal ArticleDOI
Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs).
Gilles A. Spoden,Kirsten Freitag,Matthias Husmann,Klaus Boller,Martin Sapp,Carsten Lambert,Luise Florin +6 more
TL;DR: Evidence is provided for involvement of tetraspanin-enriched microdomains (TEMs) in HPV16 endocytosis, indicating TEMs as a novel clathrin- and caveolin-independent invasion route for viral pathogens and especially HPV16.
Journal ArticleDOI
Hepatitis B Virus Maturation Is Sensitive to Functional Inhibition of ESCRT-III, Vps4, and γ2-Adaptin
TL;DR: It is demonstrated that HBV exploits the MVB machinery with the aid of γ2-adaptin, and the effects of its overexpression in virus-replicating cells are examined, hinting at different export routes used by viral and subviral particles.
Journal ArticleDOI
Identification of a Dynein Interacting Domain in the Papillomavirus Minor Capsid Protein L2
Luise Florin,Katrin A. Becker,Carsten Lambert,Thorsten Nowak,Cornelia Sapp,Dennis Strand,Rolf E. Streeck,Martin Sapp +7 more
TL;DR: It is demonstrated that the L2 protein is able to interact with the microtubule network via the motor protein dynein, indicating that this interaction mediates the minus-end-directed transport of the viral genome along microtubules towards the nucleus.
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Tetraspanin CD151 Mediates Papillomavirus Type 16 Endocytosis
Konstanze D. Scheffer,Alexander Gawlitza,Gilles A. Spoden,Xin Zhang,Carsten Lambert,Fedor Berditchevski,Luise Florin +6 more
TL;DR: Data show that complex formation of CD151 with laminin-binding integrins and integration of the complex into tetraspanin-enriched microdomains are critical for HPV16 endocytosis.
Journal ArticleDOI
Identification of the dynein light chains required for human papillomavirus infection.
TL;DR: This work identified two host cell proteins involved in HPV16 infection that are most likely required for transport purposes towards the nucleus.