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Catarina Satie Takahashi

Researcher at University of São Paulo

Publications -  62
Citations -  854

Catarina Satie Takahashi is an academic researcher from University of São Paulo. The author has contributed to research in topics: Comet assay & Micronucleus test. The author has an hindex of 17, co-authored 62 publications receiving 707 citations. Previous affiliations of Catarina Satie Takahashi include Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto.

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Potentiation by turmeric and curcumin of gamma-radiation-induced chromosome aberrations in Chinese hamster ovary cells.

TL;DR: The results clearly indicate the exacerbated effect of turmeric and curcumin on radiation-induced clastogenicity, suggesting that these antioxidants are also potentiating agents depending on the experimental conditions.
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From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease

TL;DR: The design, synthesis and evaluation of non-toxic dual binding site AChEIs by hybridization of indanone and quinoline heterocyclic scaffolds are proposed and a potent allosteric modulator of AChe able to target cholinergic and non-cholinergic functions is found by fixing a specific AchE conformation.
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Galanthamine decreases genotoxicity and cell death induced by β-amyloid peptide in SH-SY5Y cell line

TL;DR: It is demonstrated that in addition to inhibition of acetylcholinesterase (AChE), galanthamine exerts antigenotoxic properties which may improve the development of new diseases-modifying agents.