C
Catherine A. Vulfius
Researcher at Russian Academy of Sciences
Publications - 29
Citations - 345
Catherine A. Vulfius is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Acetylcholine receptor & Nicotinic agonist. The author has an hindex of 10, co-authored 29 publications receiving 301 citations. Previous affiliations of Catherine A. Vulfius include Academy of Medical Sciences, United Kingdom.
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Journal ArticleDOI
Natural compounds interacting with nicotinic acetylcholine receptors: from low-molecular weight ones to peptides and proteins.
Denis S. Kudryavtsev,Irina V. Shelukhina,Catherine A. Vulfius,Tatyana N. Makarieva,Valentin A. Stonik,Maxim N. Zhmak,Igor Ivanov,Igor E. Kasheverov,Yuri N. Utkin,Victor I. Tsetlin +9 more
TL;DR: Information on the mechanisms of nAChR interactions with the three-finger proteins of the Ly6 family was found and snake venom phospholipases A2 were recently found to inhibit different nA ChR subtypes.
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Acetylcholine receptor conformational transition on excitation masks disulphide bonds against reduction
TL;DR: A detailed study of the action of DTT on nicotinic AChRs of completely isolated Limnaea stagnalis neurones is presented in order to clarify the ability of various cholinergic ligands to protect the receptor disulphide bonds against reduction by DTT.
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Alpha-conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors.
Igor E. Kasheverov,Maxim N. Zhmak,Catherine A. Vulfius,Elena V. Gorbacheva,Dmitry Y. Mordvintsev,Yuri N. Utkin,René van Elk,August B. Smit,Victor I. Tsetlin +8 more
TL;DR: In the case of muscle‐type α‐conotoxin [D12K]SIA, the contribution of the Lys12 positive charge to enhanced affinity towards Torpedo nAChR was rationalized with the aid of computer modeling.
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Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2.
Catherine A. Vulfius,Igor E. Kasheverov,Vladislav G. Starkov,Alexey V. Osipov,T. V. Andreeva,Sergey Yu. Filkin,Elena V. Gorbacheva,Maxim E. Astashev,Victor I. Tsetlin,Yuri N. Utkin +9 more
TL;DR: Evidence is presented that phospholipases A2 from venoms of vipers Vipera ursinii and V. nikolskii, cobra Naja kaouthia, and krait Bungarus fasciatus from different snake families suppress the acetylcholine- or cytisine-elicited currents in L. stagnalis neurons and compete with α-bungarotoxin for binding to muscle- and neuronal α7-types of nicotinic acet
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An unusual phospholipase A₂ from puff adder Bitis arietans venom--a novel blocker of nicotinic acetylcholine receptors.
Catherine A. Vulfius,Elena V. Gorbacheva,Vladislav G. Starkov,Alexey V. Osipov,Igor E. Kasheverov,T. V. Andreeva,Maxim E. Astashev,Victor I. Tsetlin,Yuri N. Utkin +8 more
TL;DR: In isolation from puff adder Bitis arietans venom and characterization of a novel protein bitanarin, which is the first described PLA₂ that contains 14 disulphide bonds and the first nAChR blocker possessing PLA⁂ activity is reported.