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Irina V. Shelukhina
Researcher at Russian Academy of Sciences
Publications - 44
Citations - 693
Irina V. Shelukhina is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Nicotinic agonist & Acetylcholine receptor. The author has an hindex of 16, co-authored 41 publications receiving 541 citations. Previous affiliations of Irina V. Shelukhina include University of Eastern Finland.
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Serotonergic mechanisms of trigeminal meningeal nociception: Implications for migraine pain.
Erkan Kilinc,Erkan Kilinc,Cindy Guerrero-Toro,Andrey Zakharov,Andrey Zakharov,Carmela Vitale,Max Gubert-Olive,Ksenia Koroleva,Arina Timonina,Liliana L. Luz,Irina V. Shelukhina,Raisa Giniatullina,Fatma Tore,Boris V. Safronov,Boris V. Safronov,Rashid Giniatullin,Rashid Giniatullin +16 more
TL;DR: 5‐HT evokes powerful pro‐nociceptive peripheral and anti‐nOCiceptive central effects in trigeminal system transmitting migraine pain.
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Hunting for origins of migraine pain: cluster analysis of spontaneous and capsaicin-induced firing in meningeal trigeminal nerve fibers
Andrey Zakharov,Andrey Zakharov,Carmela Vitale,Erkan Kilinc,Erkan Kilinc,K Koroleva,K Koroleva,Dmitriy Fayuk,Irina V. Shelukhina,Nikolay Naumenko,Andrey Skorinkin,Andrey Skorinkin,Rustem Khazipov,Rustem Khazipov,Rashid Giniatullin,Rashid Giniatullin +15 more
TL;DR: The persistent activation of nociceptors in capsaicin-sensitive nerve fibers shown here may be involved in trigeminal pain signaling and plasticity along with the release of migraine-related neuropeptides from TRPV1 positive neurons.
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Neurotoxins from Snake Venoms and α-Conotoxin ImI Inhibit Functionally Active Ionotropic γ-Aminobutyric Acid (GABA) Receptors *
Denis S. Kudryavtsev,Irina V. Shelukhina,Lina V. Son,Lucy O. Ojomoko,Elena V. Kryukova,Ekaterina N. Lyukmanova,Ekaterina N. Lyukmanova,Maxim N. Zhmak,Dmitry A. Dolgikh,Dmitry A. Dolgikh,Igor Ivanov,Igor E. Kasheverov,Vladislav G. Starkov,Joachim Ramerstorfer,Werner Sieghart,Victor I. Tsetlin,Yuri N. Utkin +16 more
TL;DR: GABAA receptors are demonstrated to be inhibited by α-cobratoxin, other long chain α-neurotoxins, nonconventional toxin from Naja kaouthia, and α-conotoxin ImI, indicating that three-finger toxins offer new scaffolds for the design of GABAA receptor effectors.
Journal ArticleDOI
Natural compounds interacting with nicotinic acetylcholine receptors: from low-molecular weight ones to peptides and proteins.
Denis S. Kudryavtsev,Irina V. Shelukhina,Catherine A. Vulfius,Tatyana N. Makarieva,Valentin A. Stonik,Maxim N. Zhmak,Igor Ivanov,Igor E. Kasheverov,Yuri N. Utkin,Victor I. Tsetlin +9 more
TL;DR: Information on the mechanisms of nAChR interactions with the three-finger proteins of the Ly6 family was found and snake venom phospholipases A2 were recently found to inhibit different nA ChR subtypes.
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Peptide from Sea Anemone Metridium senile Affects Transient Receptor Potential Ankyrin-repeat 1 (TRPA1) Function and Produces Analgesic Effect.
Yulia A. Logashina,Yulia A. Logashina,Irina V. Mosharova,Yulia V. Korolkova,Irina V. Shelukhina,Igor A. Dyachenko,Victor A. Palikov,Yulia A. Palikova,A. N. Murashev,Sergey A. Kozlov,Klara Stensvåg,Yaroslav A. Andreev,Yaroslav A. Andreev +12 more
TL;DR: It is concluded that TRPA1 potentiating may be useful as a therapeutic approach as Ms 9a-1 produces significant analgesic and anti-inflammatory effects in mice models of pain.