C
Cathie Leiendecker-Foster
Researcher at University of Minnesota
Publications - 6
Citations - 348
Cathie Leiendecker-Foster is an academic researcher from University of Minnesota. The author has contributed to research in topics: Transferrin saturation & Hemochromatosis. The author has an hindex of 6, co-authored 6 publications receiving 328 citations.
Papers
More filters
Journal ArticleDOI
Pharmacogenetic Association of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on Blood Pressure and Cardiovascular Risk in Relation to Antihypertensive Treatment The Genetics of Hypertension-Associated Treatment (GenHAT) Study
Donna K. Arnett,Barry R. Davis,Charles E. Ford,Eric Boerwinkle,Cathie Leiendecker-Foster,Michael B. Miller,Henry R. Black,John H. Eckfeldt +7 more
TL;DR: It is concluded that the ACE I/D polymorphism is not a useful marker to predict antihypertensive treatment response, and was not a predictor of CHD, nor did it modify the response to antihyertensive treatment.
Journal ArticleDOI
Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in whites and blacks in the Hemochromatosis and Iron Overload Screening Study.
James C. Barton,Ronald T. Acton,Fitzroy W. Dawkins,Paul C. Adams,Laura C. Lovato,Cathie Leiendecker-Foster,Christine E. McLaren,David M. Reboussin,Mark Speechley,Victor R. Gordeuk,Gordon D. McLaren,Phyliss Sholinsky,Emily L. Harris +12 more
TL;DR: Possible explanations for differences in TfSat and SF in whites and blacks and pertinence to the detection of hemochromatosis, iron overload, and other disorders with similar phenotypes are discussed.
Journal ArticleDOI
Association between the α-adducin gene and hypertension in the HyperGEN Study
Michael A. Province,Donna K. Arnett,Steven C. Hunt,Cathie Leiendecker-Foster,John H. Eckfeldt,Albert Oberman,R. Curtis Ellison,Gerardo Heiss,Stephen C. Mockrin,Roger R. Williams +9 more
TL;DR: The α-adducin gene remained a significant independent predictor of hypertension in a multivariate logistic model even after correcting for other risk factors for hypertension, including gender, age, body mass index (BMI), smoking, LDL cholesterol, triglycerides, urine sodium (Na), and urine potassium (K), and through the use of regression trees, several gene-by-environment interactions were implicated.
Journal ArticleDOI
Comparison of the Unsaturated Iron-Binding Capacity with Transferrin Saturation as a Screening Test to Detect C282Y Homozygotes for Hemochromatosis in 101 168 Participants in the Hemochromatosis and Iron Overload Screening (HEIRS) Study
Paul C. Adams,David M. Reboussin,Cathie Leiendecker-Foster,Godfrey C. Moses,Gordon D. McLaren,Gordon D. McLaren,Christine E. McLaren,Fitzroy W. Dawkins,Ishmael Kasvosve,Ronald T. Acton,James C. Barton,Dan Zaccaro,Emily L. Harris,Richard D. Press,Henry Chang,John H. Eckfeldt +15 more
TL;DR: Screening for iron overload instead of performing DNA-based testing may reduce the risks of potential genetic discrimination that some authors suggest is associated with identification of a C282Y homozygote with normal serum iron tests.
Journal ArticleDOI
HFE C282Y homozygosity is associated with lower total and low-density lipoprotein cholesterol the Hemochromatosis and Iron Overload Screening study
Paul C. Adams,James S. Pankow,James C. Barton,Ronald T. Acton,Cathie Leiendecker-Foster,Gordon D. McLaren,Gordon D. McLaren,Mark Speechley,John H. Eckfeldt +8 more
TL;DR: The Hemochromatosis and Iron Overload Screening study as discussed by the authors showed that C282Y homozygotes had significantly lower mean total and low-density lipoprotein cholesterol concentrations than wild-type subjects.