C
Cees J. Tack
Researcher at Radboud University Nijmegen
Publications - 249
Citations - 9552
Cees J. Tack is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Diabetes mellitus & Insulin. The author has an hindex of 46, co-authored 234 publications receiving 8262 citations. Previous affiliations of Cees J. Tack include Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2.
Steef Kurstjens,Jeroen H. F. de Baaij,Jeroen H. F. de Baaij,Caro Overmars-Bos,Inge C.L. van den Munckhof,Veronica Garzero,Marijke A. de Vries,Benjamin Burggraaf,Janna A. van Diepen,Niels P. Riksen,Joost H.W. Rutten,Mihai G. Netea,Mihai G. Netea,Manuel Castro Cabezas,René J. M. Bindels,Frances M. Ashcroft,Cees J. Tack,Joost G. J. Hoenderop +17 more
TL;DR: This study shows that elevated NEFA and triacylglycerol levels directly reduce blood Mg2+ levels, in part explaining the high prevalence of hypomagnesaemia in metabolic disorders.
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Haemodynamic actions of insulin
TL;DR: Two hemodynamic actions of insulin are discussed in this review; it induces direct vasodilation in skeletal muscle: and stimulation of the sympathetic nervous system.
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Effects of Diazoxide-Mediated Insulin Suppression on Glucose and Lipid Metabolism in Nondiabetic Obese Men.
Sandra Loves,Lenneke van Groningen,Margreet Filius,Marja Mekking,Tom Brandon,Cees J. Tack,Ad R. M. M. Hermus,Hans de Boer +7 more
TL;DR: In nondiabetic obese men, insulin levels can be reduced up to 70% without major metabolic side effects, and the marked intersubject variation in maximal tolerated dose indicates that DZX dose titration needs to be individualized.
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Improving myocardial perfusion by percutaneous coronary intervention reduces central sympathetic activity in stable angina.
Marc E. Gomes,Wim R.M. Aengevaeren,Jacques W. M. Lenders,Freek W.A. Verheugt,Paul Smits,Cees J. Tack +5 more
TL;DR: By stimulating sympathetic afferents, repetitive myocardial ischemia induces a state of increased sympathetic tone.