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Célia Regina Cavichiolo Franco

Researcher at Federal University of Paraná

Publications -  62
Citations -  1112

Célia Regina Cavichiolo Franco is an academic researcher from Federal University of Paraná. The author has contributed to research in topics: Fibronectin & Endothelial stem cell. The author has an hindex of 17, co-authored 58 publications receiving 907 citations.

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Identification, cloning, expression and functional characterization of an astacin-like metalloprotease toxin from Loxosceles intermedia (brown spider) venom.

TL;DR: Sequence comparison, phylogenetic analysis and analysis of the functional recombinant toxin revealed that LALP is related in both structure and function to the astacin family of metalloproteases, suggesting that an astacIn-like toxin is present in a animal venom secretion and indicates that recombinant LALp will be a useful tool for future structural and functional studies on venom and the astACin family.
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Experimental Evidence for a Direct Cytotoxicity of Loxosceles intermedia (Brown Spider) Venom in Renal Tissue

TL;DR: Experimental evidence is provided that L. intermedia venom is directly involved in nephrotoxicity and caused azotemia with elevation of blood urea levels but did not decrease C3 complement concentration or cause hemolysis in vivo.
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Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats.

TL;DR: In this article, the authors investigated which cell types express endothelin receptors in the trigeminal ganglion, and the contribution of mechanisms mediated by ET A and ET B receptors to orofacial heat hyperalgesia induced by unilateral constriction of the infraorbital nerve (CION).
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A Non-Anticoagulant Heterofucan has Antithrombotic Activity in vivo

TL;DR: The hypothesis has been raised that the in vivo antithrombotic activity of fucan A is related to the increased production of this heparan from endothelial cells like heparin, and the data suggest that it may be an ideal antithromabotic agent in vivo.