B
Barbora Hermankova
Researcher at Academy of Sciences of the Czech Republic
Publications - 26
Citations - 393
Barbora Hermankova is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 10, co-authored 26 publications receiving 273 citations. Previous affiliations of Barbora Hermankova include Charles University in Prague.
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A Comparative Study of the Therapeutic Potential of Mesenchymal Stem Cells and Limbal Epithelial Stem Cells for Ocular Surface Reconstruction
Vladimir Holan,Vladimir Holan,Peter Trosan,Peter Trosan,Cestmir Cejka,Cestmir Cejka,Eliska Javorkova,Eliska Javorkova,Alena Zajicova,Barbora Hermankova,Barbora Hermankova,Milada Chudíčková,Milada Chudíčková,Jitka Cejkova +13 more
TL;DR: Results show that BM‐MSCs' therapeutic effect on healing of injured corneal surface is comparable to that of tissue‐specific LSCs, and suggest that BM-MSCs can be used for ocular surface regeneration in cases when autologous L SCs are absent or difficult to obtain.
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Suppression of IL-10 production by activated B cells via a cell contact-dependent cyclooxygenase-2 pathway upregulated in IFN-γ-treated mesenchymal stem cells
Barbora Hermankova,Alena Zajicova,Eliska Javorkova,Milada Chudíčková,Peter Trosan,Michaela Hajkova,Magdalena Krulova,Vladimir Holan,Vladimir Holan +8 more
TL;DR: IFN-γ-treated MSCs strongly inhibit IL-10 production by activated B cells by a mechanism requiring cell contact and involving the Cox-2 pathway, and the production ofIL-10 by B cells was inhibited by exogenous prostaglandin E2.
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Distinct Immunoregulatory Mechanisms in Mesenchymal Stem Cells: Role of the Cytokine Environment
Vladimir Holan,Vladimir Holan,Barbora Hermankova,Barbora Hermankova,Pavla Bohacova,Pavla Bohacova,Jan Kossl,Jan Kossl,Milada Chudíčková,Milada Chudíčková,Michaela Hajkova,Michaela Hajkova,Magdalena Krulova,Magdalena Krulova,Alena Zajicova,Eliska Javorkova,Eliska Javorkova +16 more
TL;DR: The results show that MSCs can inhibit the response of B cells to one stimulus by different mechanisms in dependence on the cytokine environment and thus support the idea of the complexity of immunoregulatory action of M SCs.
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Mesenchymal Stem Cell-Based Therapy for Retinal Degenerative Diseases: Experimental Models and Clinical Trials.
TL;DR: In this article, the mesenchymal stem cells (MSC) are used for the treatment of retinal degenerative diseases. But, despite considerable efforts, the treatment possibilities for these disorders remain very limited.
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Mesenchymal Stem Cells Attenuate the Adverse Effects of Immunosuppressive Drugs on Distinct T Cell Subopulations
Michaela Hajkova,Michaela Hajkova,Barbora Hermankova,Barbora Hermankova,Eliska Javorkova,Eliska Javorkova,Pavla Bohacova,Pavla Bohacova,Alena Zajicova,Vladimir Holan,Vladimir Holan,Magdalena Krulova,Magdalena Krulova +12 more
TL;DR: The results indicated that MSC-based therapy could be a powerful strategy to attenuate the negative effects of immunosuppressive drugs on the immune system.