E
Eliska Javorkova
Researcher at Academy of Sciences of the Czech Republic
Publications - 29
Citations - 634
Eliska Javorkova is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 12, co-authored 25 publications receiving 472 citations. Previous affiliations of Eliska Javorkova include Charles University in Prague.
Papers
More filters
Journal ArticleDOI
A Comparative Study of the Therapeutic Potential of Mesenchymal Stem Cells and Limbal Epithelial Stem Cells for Ocular Surface Reconstruction
Vladimir Holan,Vladimir Holan,Peter Trosan,Peter Trosan,Cestmir Cejka,Cestmir Cejka,Eliska Javorkova,Eliska Javorkova,Alena Zajicova,Barbora Hermankova,Barbora Hermankova,Milada Chudíčková,Milada Chudíčková,Jitka Cejkova +13 more
TL;DR: Results show that BM‐MSCs' therapeutic effect on healing of injured corneal surface is comparable to that of tissue‐specific LSCs, and suggest that BM-MSCs can be used for ocular surface regeneration in cases when autologous L SCs are absent or difficult to obtain.
Journal ArticleDOI
Suppression of alkali-induced oxidative injury in the cornea by mesenchymal stem cells growing on nanofiber scaffolds and transferred onto the damaged corneal surface.
Jitka Cejkova,Peter Trosan,Peter Trosan,Cestmir Cejka,Cestmir Cejka,A Lencova,Alena Zajicova,Eliska Javorkova,Eliska Javorkova,Šárka Kubinová,Eva Syková,Vladimir Holan,Vladimir Holan +12 more
TL;DR: MSCs on nanofiber scaffolds protected the formation of toxic peroxynitrite, lowered apoptotic cell death and decreased matrix metalloproteinase and pro-inflammatory cytokine production and significantly accelerated corneal healing.
Journal ArticleDOI
The Favorable Effect of Mesenchymal Stem Cell Treatment on the Antioxidant Protective Mechanism in the Corneal Epithelium and Renewal of Corneal Optical Properties Changed after Alkali Burns
Cestmir Cejka,Vladimir Holan,Vladimir Holan,Peter Trosan,Peter Trosan,Alena Zajicova,Eliska Javorkova,Eliska Javorkova,Jitka Cejkova +8 more
TL;DR: In conclusion, stem cell treatment accelerated regeneration of the corneal epithelium, restored the antioxidant protective mechanism, and renewed cornea optical properties after alkali burns.
Journal ArticleDOI
Mesenchymal stem cells, nanofiber scaffolds and ocular surface reconstruction.
TL;DR: The transplantation of autologous mesenchymal stem cells (MSCs) represents a promising therapeutic approach and offers hope for patients with severe ocular surface injuries and LSC deficiency.
Journal ArticleDOI
Suppression of IL-10 production by activated B cells via a cell contact-dependent cyclooxygenase-2 pathway upregulated in IFN-γ-treated mesenchymal stem cells
Barbora Hermankova,Alena Zajicova,Eliska Javorkova,Milada Chudíčková,Peter Trosan,Michaela Hajkova,Magdalena Krulova,Vladimir Holan,Vladimir Holan +8 more
TL;DR: IFN-γ-treated MSCs strongly inhibit IL-10 production by activated B cells by a mechanism requiring cell contact and involving the Cox-2 pathway, and the production ofIL-10 by B cells was inhibited by exogenous prostaglandin E2.