C
Cha-Gyun Jung
Researcher at Nagoya City University
Publications - 52
Citations - 1667
Cha-Gyun Jung is an academic researcher from Nagoya City University. The author has contributed to research in topics: Neural stem cell & Medicine. The author has an hindex of 22, co-authored 45 publications receiving 1483 citations. Previous affiliations of Cha-Gyun Jung include Japan Society for the Promotion of Science & University of Chicago.
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Journal ArticleDOI
FTY720 modulates human oligodendrocyte progenitor process extension and survival.
Veronique E. Miron,Cha-Gyun Jung,Hye-Jung Kim,Timothy E. Kennedy,Betty Soliven,Jack P. Antel +5 more
TL;DR: The objective was to assess the effect of FTY720 on process extension, differentiation, and survival of human oligodendrocyte progenitor cells (OPCs), and link the functional effects with S1P receptor expression and signaling.
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Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells
Cha-Gyun Jung,Hye-Jung Kim,Veronique E. Miron,S Cook,Timothy E. Kennedy,C A Foster,Jack P. Antel,Betty Soliven +7 more
TL;DR: S1P1 and S1P5 serve different functions during oligodendroglial development, and possibly during remyelination, as well as being differentially modulated by platelet‐derived growth factor (PDGF) and PDGF‐induced OPC mitogenesis.
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Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells.
TL;DR: Although GDNF did not promote the differentiation of purified SCs into the myelinating phenotype, it enhanced myelination in neuron–SC cocultures and it is concluded that GDNF utilizes NCAM signaling pathways to regulate SC function prior toMyelination and at early stages of myelin formation.
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Pleiotrophin exhibits a trophic effect on survival of dopaminergic neurons in vitro.
Hideki Hida,Hideki Hida,Cha-Gyun Jung,Cha-Gyun Jung,Chen-Zhen Wu,Hye-Jung Kim,Yuji Kodama,Tadashi Masuda,Hitoo Nishino,Hitoo Nishino +9 more
TL;DR: The data indicate that PTN is up‐regulated in DA‐depleted striatum and exhibits a trophic effect specifically on the survival of cultured dopaminergic neurons.
Journal ArticleDOI
Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation.
Cha-Gyun Jung,Hye-Jung Kim,Makoto Kawaguchi,Kum Kum Khanna,Hideki Hida,Kiyofumi Asai,Hitoo Nishino,Yutaka Miura +7 more
TL;DR: It is proposed that ATBF1 plays an important role in the nucleus by organizing the neuronal differentiation associated with the cell cycle arrest.