C
Chandran Ragunath
Researcher at Rutgers University
Publications - 30
Citations - 2991
Chandran Ragunath is an academic researcher from Rutgers University. The author has contributed to research in topics: Dispersin B & Biofilm. The author has an hindex of 19, co-authored 30 publications receiving 2753 citations. Previous affiliations of Chandran Ragunath include University of Medicine and Dentistry of New Jersey.
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Journal ArticleDOI
Polysaccharide intercellular adhesin or protein factors in biofilm accumulation of Staphylococcus epidermidis and Staphylococcus aureus isolated from prosthetic hip and knee joint infections.
Holger Rohde,Eike Burandt,Nicolaus Siemssen,Lars Frommelt,Christoph Burdelski,Sabine Wurster,Stefanie Scherpe,Angharad P. Davies,Llinos G. Harris,Matthias A. Horstkotte,Johannes K.-M. Knobloch,Chandran Ragunath,Jeffrey B. Kaplan,Dietrich Mack +13 more
TL;DR: PIA and protein factors like Aap are of differential importance for the pathogenesis of S. aureus and protein-dependent biofilms were exclusively found in S. epidermidis strains isolated from prosthetic joint infections after total hip or total knee arthroplasty.
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Detachment of Actinobacillus actinomycetemcomitans Biofilm Cells by an Endogenous β-Hexosaminidase Activity
TL;DR: It is concluded that dspB encodes a soluble beta-N-acetylglucosaminidase that causes detachment and dispersion of A. actinomycetemcomitans biofilm cells.
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Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D3
TL;DR: Elucidation of the effect of 1,25(OH)(2)D(3) on cathelicidin expression in NHBE cells and CF bronchial epithelial cells will aid in the development of novel therapeutic agents for treatment of airway infections in CF.
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Enzymatic Detachment of Staphylococcus epidermidis Biofilms
Jeffrey B. Kaplan,Chandran Ragunath,Kabilan Velliyagounder,Daniel H. Fine,Narayanan Ramasubbu +4 more
TL;DR: It is found that a biofilm-releasing enzyme produced by the gram-negative periodontal pathogen Actinobacillus actinomycetemcomitans rapidly and efficiently removed S. epidermidis biofilms from plastic surfaces.
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Genes involved in the synthesis and degradation of matrix polysaccharide in Actinobacillus actinomycetemcomitans and Actinobacillus pleuropneumoniae biofilms.
Jeffrey B. Kaplan,Kabilan Velliyagounder,Chandran Ragunath,Holger Rohde,Dietrich Mack,Johannes K.-M. Knobloch,Narayanan Ramasubbu +6 more
TL;DR: It is confirmed that PGA functions as a biofilm matrix polysaccharide in phylogenetically diverse bacterial species and suggested that P GA may play a role in intercellular adhesion and cellular detachment and dispersal in A. pleuropneumoniae biofilms.