Jeffrey B. Kaplan

TL;DR: The current status of research on biofilm dispersal is described, with an emphasis on studies aimed to characterize dispersal mechanisms, and to identify environmental cues and inter- and intracellular signals that regulate the dispersal process.

TL;DR: It is concluded that PNAG and ecDNA play fundamentally different structural roles in S. aureus and S. epidermidis biofilms, which are major human pathogens of increasing importance due to the dissemination of antibiotic-resistant strains.

TL;DR: PIA and protein factors like Aap are of differential importance for the pathogenesis of S. aureus and protein-dependent biofilms were exclusively found in S. epidermidis strains isolated from prosthetic joint infections after total hip or total knee arthroplasty.

TL;DR: It is concluded that dspB encodes a soluble beta-N-acetylglucosaminidase that causes detachment and dispersion of A. actinomycetemcomitans biofilm cells.

TL;DR: This article reviews studies demonstrating that low-dose antibiotics induce bacterial biofilm formation and the signaling pathways involved in global gene regulation in response to cell stressors and concludes that it is still unclear whether antibiotic-inducedBiofilm formation contributes to the inconsistent success of antimicrobial therapy for device infections.