C
Chang-Deng Hu
Researcher at Purdue University
Publications - 72
Citations - 6849
Chang-Deng Hu is an academic researcher from Purdue University. The author has contributed to research in topics: Bimolecular fluorescence complementation & Prostate cancer. The author has an hindex of 37, co-authored 71 publications receiving 6267 citations. Previous affiliations of Chang-Deng Hu include University of Michigan & Kobe University.
Papers
More filters
Journal ArticleDOI
Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation
TL;DR: Results attest to the general applicability of the BiFC assay for studies of protein interactions.
Journal ArticleDOI
Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis.
Chang-Deng Hu,Tom K. Kerppola +1 more
TL;DR: A bimolecular fluorescence complementation approach for the simultaneous visualization of multiple protein interactions in the same cell based on complementation between fragments of fluorescent proteins with different spectral characteristics is described.
Journal ArticleDOI
Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions.
TL;DR: The identification of new fluorescent protein fragments derived from Venus and Cerulean for BiFC and multicolor BiFC assays under physiological culture conditions exhibit a 13-fold higher BiFC efficiency than originally identified fragmentsderived from YFP.
Journal ArticleDOI
Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis
Megan M. Young,Yoshinori Takahashi,Osman Khan,Sungman Park,Tsukasa Hori,Jong K. Yun,Arun Sharma,Shantu Amin,Chang-Deng Hu,Jianke Zhang,Mark Kester,Hong Gang Wang +11 more
TL;DR: An autophagy-dependent mechanism of caspase-8 activation and initiation of the apoptotic cascade in response to SKI-I, a pan-sphingosine kinase inhibitor, and bortezomib, a proteasome inhibitor is demonstrated.
Journal ArticleDOI
Bimolecular fluorescence complementation (BiFC): A 5-year update and future perspectives
Yutaka Kodama,Chang-Deng Hu +1 more
TL;DR: Current BiFC technology is reviewed, focusing on the development and improvement of BiFC systems, the understanding of split sites in fluorescent proteins, and enhancements in the signal-to-noise ratio.