C
Changquan Calvin Sun
Researcher at University of Minnesota
Publications - 248
Citations - 10301
Changquan Calvin Sun is an academic researcher from University of Minnesota. The author has contributed to research in topics: Tableting & Cocrystal. The author has an hindex of 45, co-authored 223 publications receiving 8070 citations. Previous affiliations of Changquan Calvin Sun include Pharmacia & Pfizer.
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Influence of Crystal Shape on the Tableting Performance of L‐Lysine Monohydrochloride Dihydrate
TL;DR: The greater tabletability of T is a result of its better compactibility that overcomes the negative effects by its lower compressibility, related to favorable orientation of the slip planes in the tablet, corresponding to greater plasticity under load.
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Exceptionally Elastic Single-Component Pharmaceutical Crystals
TL;DR: The first elastically bendable single-component pharmaceutical crystal, celecoxib, was reported in this paper, which exhibited both therapeutic effects and elastic mechanical behavior, and could be used to manufacture functional microdevices with novel medical applications.
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Quantifying effects of moisture content on flow properties of microcrystalline cellulose using a ring shear tester
TL;DR: In this article, the effects of moisture content over the relative humidity (RH) range of 5-92% corresponding to 1.6-10.9% of water content, on flow properties of a grade of microcrystalline cellulose (Avicel PH102) using a ring shear cell.
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Mini review: Mechanisms to the loss of tabletability by dry granulation
TL;DR: This mini-review has critically examined literature aimed at understanding the mechanisms to the frequently observed phenomenon of loss of tabletability of a powder after dry granulation by slugging or roll compaction and summarized a total of eight important aspects that should be addressed when developing a drygranulation (DG) process.
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On the identification of slip planes in organic crystals based on attachment energy calculation.
Changquan Calvin Sun,Y.-H. Kiang +1 more
TL;DR: Predicting slip/cleavage planes by attachment energy calculation may not be always accurate and should be treated with caution, as these crystallographic planes can be identified by visualization of crystals characterized by stacking layers of high molecular density and often strengthened by two-dimensional hydrogen bonding network.