C
Chao Jiang
Researcher at Johns Hopkins University School of Medicine
Publications - 31
Citations - 918
Chao Jiang is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 14 publications receiving 584 citations. Previous affiliations of Chao Jiang include Zhengzhou University.
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Journal ArticleDOI
Inhibition of neuronal ferroptosis protects hemorrhagic brain
Qian Li,Xiaoning Han,Xi Lan,Yufeng Gao,Jieru Wan,Frederick Durham,Tian Cheng,Jie Yang,Zhongyu Wang,Chao Jiang,Mingyao Ying,Raymond C. Koehler,Brent R. Stockwell,Jian Wang +13 more
TL;DR: It is found that administration of ferrostatin-1, a specific inhibitor of ferroptosis, prevented neuronal death and reduced iron deposition induced by hemoglobin in organotypic hippocampal slice cultures (OHSCs) and human induced pluripotent stem cell-derived neurons better than any inhibitor alone.
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Cerebral ischemia increases bone marrow CD4+CD25+FoxP3+ regulatory T cells in mice via signals from sympathetic nervous system
Jianping Wang,Lie Yu,Chao Jiang,Xiaojie Fu,Xi Liu,Menghan Wang,Chunying Ou,Xiaobing Cui,Chengguang Zhou,Jian Wang +9 more
TL;DR: It is concluded that cerebral ischemia can increase bone marrow CD4(+)CD25(+)FoxP3(+) regulatory T cells via signals from the sympathetic nervous system and the disruption of the CXCR4-SDF-1 axis may facilitate mobilization of Treg cells and other CX CR4(+) cells into peripheral blood.
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Cerebroprotection by the neuronal PGE2 receptor EP2 after intracerebral hemorrhage in middle-aged mice.
TL;DR: The premise that neuronal EP2 receptor activation by PGE2 protects brain against ICH injury in middle-aged mice through its anti-inflammatory and anti-oxidant effects andAnti-MMP-2/9 activity is supported.
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Bone marrow mononuclear cells exert long-term neuroprotection in a rat model of ischemic stroke by promoting arteriogenesis and angiogenesis
TL;DR: The data indicate that BMMNCs can significantly enhance arteriogenesis and angiogenesis, reduce infarct volume, and promote long-term functional recovery after pMCAO in rats.
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Progesterone Changes VEGF and BDNF Expression and Promotes Neurogenesis After Ischemic Stroke
TL;DR: The data suggest that the enhancement of endogenous BDNF and subsequent neurogenesis could partially underlie the neuroprotective effects of progesterone.