C
Charles B. Foster
Researcher at Cleveland Clinic
Publications - 60
Citations - 4425
Charles B. Foster is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 25, co-authored 56 publications receiving 4190 citations. Previous affiliations of Charles B. Foster include Advanced Technology Center & Cleveland Clinic Lerner Research Institute.
Papers
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Journal ArticleDOI
Chronic granulomatous disease. Report on a national registry of 368 patients.
Jerry A. Winkelstein,Mary C. Marino,Richard B. Johnston,John Boyle,John T. Curnutte,John I. Gallin,Harry L. Malech,S.M. Holland,Hans D. Ochs,Paul G. Quie,Rebecca H. Buckley,Charles B. Foster,S. J. Chanock,Howard B. Dickler +13 more
TL;DR: A registry of United States residents with chronic granulomatous disease (CGD) was established in 1993 in order to estimate the minimum incidence of this uncommon primary immunodeficiency disease and characterize its epidemiologic and clinical features.
PatentDOI
Single nucleotide polymorphic discrimination by electronic dot blot assay on semiconductor microchips
TL;DR: In this paper, a rapid SNP detection method was proposed that utilizes electronic circuitry on silicon microchips, which provides accurate discrimination of amplified DNA samples following electronic assisted transport, concentration and attachment of DNA to selected electrodes (test sites).
Journal ArticleDOI
Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease.
Charles B. Foster,Thomas Lehrnbecher,Femke Mol,Seth M. Steinberg,David Venzon,Thomas J. Walsh,Deborah Noack,Julie Rae,Jerry A. Winkelstein,John T. Curnutte,John T. Curnutte,Stephen J. Chanock +11 more
TL;DR: To identify genetic modifiers of disease severity, a cohort of 129 CGD patients was studied and seven candidate genes, each containing a physiologically relevant polymorphism predicted to influence the host inflammatory response, were selected.
Journal ArticleDOI
Variant Genotypes of the Low-Affinity Fcγ Receptors in Two Control Populations and a Review of Low-Affinity Fcγ Receptor Polymorphisms in Control and Disease Populations
Thomas Lehrnbecher,Charles B. Foster,Shaoxian Zhu,Susan F. Leitman,Lynn R. Goldin,Konrad Huppi,Stephen J. Chanock +6 more
TL;DR: Data is presented that should serve as the foundation for the interpretation of association studies involving multiple variant alleles of the low-affinity FcgammaR.
Journal ArticleDOI
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.
Terrance P. O'Hanlon,Danielle M. Carrick,Ira N. Targoff,Frank C. Arnett,John D. Reveille,Mary Carrington,Xiaojiang Gao,Chester V. Oddis,Penelope A. Morel,James D. Malley,Karen G. Malley,Ejaz A. Shamim,Lisa G. Rider,Stephen J. Chanock,Charles B. Foster,Thomas J Bunch,Perry J. Blackshear,Paul H. Plotz,Lori A. Love,Frederick W. Miller +19 more
TL;DR: It is demonstrated that HLA signatures, comprising both risk and protective alleles or motifs, distinguish IIM patients with different myositis autoantibodies and may have diagnostic and pathogenic implications.