C
Charles E. Murry
Researcher at University of Washington
Publications - 290
Citations - 46975
Charles E. Murry is an academic researcher from University of Washington. The author has contributed to research in topics: Induced pluripotent stem cell & Stem cell. The author has an hindex of 85, co-authored 270 publications receiving 43033 citations. Previous affiliations of Charles E. Murry include Duke University & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems
Jonathan H. Tsui,Andrea Leonard,Nathan D. Camp,Joseph T. Long,Zeid Y. Nawas,Rakchanok Chavanachat,Alec S.T. Smith,Jong Seob Choi,Zhipeng Dong,Eun Hyun Ahn,Alejandro Wolf-Yadlin,Charles E. Murry,Nathan J. Sniadecki,Deok Ho Kim +13 more
TL;DR: In this paper, a hybrid hydrogel comprised of decellularized porcine myocardial extracellular matrix (dECM) and reduced graphene oxide (rGO) was developed to provide a more instructive microenvironment for proper cell and tissue development.
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Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells.
Jay Gantz,Nathan J. Palpant,Robert E. Welikson,Stephen D. Hauschka,Charles E. Murry,Michael A. Laflamme +5 more
TL;DR: Zinc finger nuclease technology is used to stably insert a unique, selectable, floxed dual-fluorescence reporter transgene into the AAVS1 locus of RUES2 hESCs, a useful new tool for both in vitro fate mapping studies and the selection of useful differentiated cell types.
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Monocyte Chemoattractant Protein 1–Mediated Migration of Mesenchymal Stem Cells Is a Source of Intimal Hyperplasia
Monika K. Grudzinska,Ewa Kurzejamska,Krzysztof Bojakowski,Joanna Soin,Michael H. Lehmann,Hans Reinecke,Charles E. Murry,Cecilia Söderberg-Nauclér,Piotr Religa +8 more
TL;DR: The adventitia is a potentially important cellular source that contributes to intimal hyperplasia, and MCP-1 is a potent chemokine for the recruitment of adventitial vascular progenitor cells to intima lesions.
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Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling
Peter Hofsteen,Aaron M. Robitaille,Daniel Patrick Chapman,Randall T. Moon,Randall T. Moon,Charles E. Murry +5 more
TL;DR: This work reveals a regulator of cardiac development, Disabled 2, and found that in zebrafish embryos, it negatively regulates WNT/β-catenin signaling to promote cardiomyocyte differentiation, revealing a highly conserved, previously unidentified process relevant for human heart development.
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Transgenic overexpression of ribonucleotide reductase improves cardiac performance
Sarah G. Nowakowski,Stephen C. Kolwicz,Frederick S. Korte,Zhaoxiong Luo,Jacqueline N. Robinson-Hamm,Jennifer L. Page,Frank V. Brozovich,Robert S. Weiss,Rong Tian,Charles E. Murry,Michael Regnier +10 more
TL;DR: Long-term elevation of cardiac [dATP] results in sustained elevation of basal left ventricular performance, with maintained β-adrenergic responsiveness and energetic reserves, and is concluded that this occurs primarily via enhanced myofilament activation and contraction.