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Charles E. Murry

Researcher at University of Washington

Publications -  290
Citations -  46975

Charles E. Murry is an academic researcher from University of Washington. The author has contributed to research in topics: Induced pluripotent stem cell & Stem cell. The author has an hindex of 85, co-authored 270 publications receiving 43033 citations. Previous affiliations of Charles E. Murry include Duke University & Fred Hutchinson Cancer Research Center.

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VEGF Induces Differentiation of Functional Endothelium From Human Embryonic Stem Cells Implications for Tissue Engineering

TL;DR: The ability of hESC-derived endothelial cells to facilitate vascularization of tissue-engineered implants is demonstrated, and this enrichment method increases endothelial cell yield, enabling applications for revascularization as well as basic studies of human endothelial biology.
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Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms.

TL;DR: The evidence for potential mechanisms underlying the benefits of cell transplantation in the heart and the clinical contexts in which they may be relevant are reviewed.
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Fibroblast Growth Factor-2 Regulates Myocardial Infarct Repair : Effects on Cell Proliferation, Scar Contraction, and Ventricular Function

TL;DR: FGF2 is an important regulator of cell proliferation, angiogenesis, collagen synthesis, myocyte hypertrophy, scar contraction, and, ultimately, left ventricular contractile function during infarct repair and may be more important in healing ofinfarcts compared with skin wounds because of the mechanical stress under which infarCTs heal.
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Human Organ-Specific Endothelial Cell Heterogeneity.

TL;DR: The link between human EC heterogeneity and organ development is shown and can be exploited therapeutically to contribute in organ regeneration, disease modeling, as well as guiding differentiation of tissue-specific ECs from human pluripotent stem cells.