C
Charles H. Kellner
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 344
Citations - 9169
Charles H. Kellner is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Electroconvulsive therapy & Depression (differential diagnoses). The author has an hindex of 40, co-authored 335 publications receiving 8341 citations. Previous affiliations of Charles H. Kellner include Medical University of South Carolina & University of Medicine and Dentistry of New Jersey.
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Journal ArticleDOI
Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications.
Phillip W. Gold,D. L. Loriaux,Alec Roy,Mitchell Kling,Joseph R. Calabrese,Charles H. Kellner,Lynnette K. Nieman,Post Rm,David Pickar,William T. Gallucci +9 more
TL;DR: The pathophysiologic features of hypercortisolism in depression and Cushing's disease are distinct in each of the disorders and that the ovine corticotropin-releasing hormone stimulation test can be helpful in their differential diagnosis.
Journal ArticleDOI
Psychiatric implications of basic and clinical studies with corticotropin-releasing factor.
Philip W. Gold,George P. Chrousos,Charles H. Kellner,Robert M. Post,Alec Roy,P Augerinos,Heinrich M. Schulte,Edward H. Oldfield,D. L. Loriaux +8 more
TL;DR: Clinically, experience in administering ovine CRF shows that CRF can be helpful in resolving differential diagnostic dilemmas in patients with various disorders of the hypothalamic-pituitary-adrenal axis and in furthering an understanding of the pathophysiology of conditions such as Cushing's disease and depression.
Journal ArticleDOI
Continuation Electroconvulsive Therapy vs Pharmacotherapy for Relapse Prevention in Major Depression: A Multisite Study From the Consortium for Research in Electroconvulsive Therapy (CORE)
Charles H. Kellner,Rebecca G. Knapp,Georgios Petrides,Teresa A. Rummans,Mustafa M. Husain,Keith G. Rasmussen,Martina Mueller,Hilary J. Bernstein,Kevin C. O’Connor,Glenn E. Smith,Melanie M. Biggs,Samuel H. Bailine,Chitra Malur,Eunsil Yim,Shawn M. McClintock,Shirlene Sampson,Max Fink +16 more
TL;DR: Both C-ECT and C-Pharm were shown to be superior to a historical placebo control, but both had limited efficacy, with more than half of patients either experiencing disease relapse or dropping out of the study.
Journal ArticleDOI
ECT remission rates in psychotic versus nonpsychotic depressed patients: a report from CORE.
Georgios Petrides,Max Fink,Mustafa M. Husain,Rebecca G. Knapp,A. John Rush,Martina Mueller,Teresa A. Rummans,Kevin O'Connor,Keith G. Rasmussen,Hilary J. Bernstein,Melanie M. Biggs,Samuel H. Bailine,Charles H. Kellner +12 more
TL;DR: Bilateral ECT is effective in relieving severe major depression andRemission rates are higher and occur earlier in psychotic depressed patients than in nonpsychotic depressed patients, supporting the argument that psychotic depression is a distinguishable nosological entity that warrants separate treatment algorithms.
Journal ArticleDOI
Speed of response and remission in major depressive disorder with acute electroconvulsive therapy (ECT): a Consortium for Research in ECT (CORE) report.
Mustafa M. Husain,A. John Rush,Max Fink,Rebecca G. Knapp,Georgios Petrides,Teresa A. Rummans,Melanie M. Biggs,Kevin O'Connor,Keith G. Rasmussen,Marc Litle,Wenle Zhao,Hilary J. Bernstein,Glenn E. Smith,Martina Mueller,Shawn M. McClintock,Samuel H. Bailine,Charles H. Kellner,Charles H. Kellner +17 more
TL;DR: ECT was associated with rapid response and remission in a high percentage of patients and warrants early consideration in treatment algorithms for patients with MDD.