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Chen Ding
Researcher at Fudan University
Publications - 1
Citations - 248
Chen Ding is an academic researcher from Fudan University. The author has contributed to research in topics: Autophagosome & Autophagy. The author has an hindex of 1, co-authored 1 publications receiving 108 citations.
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Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds
Zhaoyang Li,Cen Wang,Ziying Wang,Chenggang Zhu,Jie Li,Tian Sha,Lixiang Ma,Chao Gao,Yi Yang,Yimin Sun,Jian Wang,Xiaoli Sun,Chenqi Lu,Marian DiFiglia,Yan-Ai Mei,Chen Ding,Shouqing Luo,Yongjun Dang,Yu Ding,Yiyan Fei,Boxun Lu +20 more
TL;DR: Compounds that interact with mutant huntingtin and an autophagosomal protein are able to reduce cellular levels of mutant Huntingtin by targeting it for autophagic degradation, demonstrating an approach that may have potential for treating proteopathies.