Z
Ziying Wang
Researcher at Fudan University
Publications - 2
Citations - 296
Ziying Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Autophagosome & Autophagy. The author has an hindex of 2, co-authored 2 publications receiving 113 citations.
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Journal ArticleDOI
Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds
Zhaoyang Li,Cen Wang,Ziying Wang,Chenggang Zhu,Jie Li,Tian Sha,Lixiang Ma,Chao Gao,Yi Yang,Yimin Sun,Jian Wang,Xiaoli Sun,Chenqi Lu,Marian DiFiglia,Yan-Ai Mei,Chen Ding,Shouqing Luo,Yongjun Dang,Yu Ding,Yiyan Fei,Boxun Lu +20 more
TL;DR: Compounds that interact with mutant huntingtin and an autophagosomal protein are able to reduce cellular levels of mutant Huntingtin by targeting it for autophagic degradation, demonstrating an approach that may have potential for treating proteopathies.
Journal ArticleDOI
Degradation of lipid droplets by chimeric autophagy-tethering compounds
TL;DR: In this paper, the autophagy-tethering compounds (ATTECs) were used to degrade non-protein biomolecules by using lipid droplets (LDs) as an exemplar target.