Showing papers in "Biomacromolecules in 2019"

TL;DR: It appears that the use of nanocellulose for these applications as an adsorbent and as a membrane for the removal of contaminants is very promising for wastewater treatment industries.

TL;DR: In this review, it is summarized the fabrication, characterization, and potential challenges and future perspectives of newly reported thermosensitive hydrogels as cartilage tissue engineering scaffolds.

TL;DR: This Review focuses on determining correlations between brushlike architectures and materials properties and investigates the relationship between molecular size, anisotropic conformation, and reduced chain entanglement.

TL;DR: This work utilizes a variety of softwood Kraft lignin morphologies to obtain strong and ductile CNF nanocomposite films and concludes that homogeneously distributed CLPs act as ball bearing lubricating and stress transferring agents in the CNF matrix.

TL;DR: High stretchable (tensile strain ∼126%) and compressible (compression strain ∼80%) cellulose ionic hydrogels (CIHs) among pure natural polymer-based hydrogel including cellulose, chitin, and chitosan via chemical cross-linking based on free radical polymerization of allyl cellulose in NaOH/urea aqueous solution are reported.

TL;DR: In this review, ROS-responsive nanocarriers, prodrugs, and supramolecular hydrogels are summarized in terms of their application for drug/gene delivery, and common strategies to elevate or diminish cellular ROS concentrations were discussed.

TL;DR: Mixed thermoreversible gels were successfully fabricated by the addition of a thermosensitive polymer, poly(N-isopropylacrylamide) (PNIPAM), to fibrillar nanostructures self-assembled from a short peptide I3K to mimic the extracellular matrix and could potentially be used as injectable hydrogels for minimally invasive drug delivery or tissue engineering.

TL;DR: In this study, a tissue-engineered trachea, consisting of multilevel structural electrospun polylactide (PLA) membranes enveloping 3D-printed thermoplastic polyurethane (TPU) skeletons, was developed to create a mechanically robust, antibacterial and bioresorbable graft for the tracheal reconstruction.

TL;DR: The history of resorbable polymers containing glycolide, lactide, ε-caprolactone and trimethylene carbonate, with a special emphasis being placed on the time frame of the 1960s-1990s is described, highlighting the visionary role played by the pioneers.

TL;DR: The concentrations and molecular weights of the constituent polymers were found to be critical parameters affecting the flow and mechanical properties of the self-healing hydrogels, which showed great potential as bioinks for fabricating cell-laden structures using a 3D printer.

TL;DR: This work developed a strategy for constructing polymer brushes with hierarchical architecture on polyurethane (PU) via surface-initiated atom-transfer radical polymerization (SI-ATRP), which possessed persistent antifouling and bactericidal performances both under static and hydrodynamic conditions.

TL;DR: Both the strength and toughness of DCH was enhanced, and the dual networks consisting of short-chain and long-chain cross-linking played an important role in the improvement of the mechanical properties of the cellulose hydrogels.

TL;DR: This study provided a facile and effective strategy of highly stable coordination-mediated polymeric nanoparticles for combinational therapy of cancer and demonstrated that the Cu(II)/DDC-loaded nanoparticles showed superior antitumor efficacy to DSF/Cu(II.

TL;DR: Light-responsive multifunctional nanoparticles with conjugation of quaternary ammonium chitosan and photosensitizer chlorin e6 (Ce6) to merge chemical and photodynamic therapy to efficient anti-bacteria to represent a promising class of antimicrobial strategy for potential clinical translation.

TL;DR: As modified PEF materials possessing superior thermo-mechanical and O2 gas barrier properties, these integrally biobased copolyesters may find practical applications in eco-packaging and other fields.

TL;DR: The hydrogel was shown to be cytocompatible (neuronal cells, in vitro) and injectable through a small-gauge needle (in vivo in rats) and displays highly attractive features for use in brain/soft tissue engineering as well as in drug delivery.

TL;DR: The zero-shear viscosity of the resins was found to be temperature-dependent and follow a linear Arrhenius relationship, and the study of these parameters and their influence the cDLP 3D printing process and the resulting mechanical properties is reported.

TL;DR: The performance of acetylated nanocellulose bioinks opens the possibility for reliable and scale-up fabrication of scaffolds appropriate for studies on cellular processes and for tissue engineering.

TL;DR: A newly discovered function of lignin mediating the formation of human bone-like HAp is reported, which exhibits many attractive properties for medical applications, including high durability, stability, antioxidant and antibacterial activities, and biocompatibility.

TL;DR: Results unravel the potential of PLGA nanoparticles as a reliable delivery system of AMPs to lungs for treatment of Pseudomonas aeruginosa lung infections in cystic fibrosis sufferers.

TL;DR: This Review provides a summary of the state-of-the-art in the development of designed ordered protein assemblies, which have exceptional potential as advanced bionanomaterials for a diversity of applications.

TL;DR: The results indicate that this composite fibrous membrane exhibits significant potential for guided bone or tissue regeneration.

TL;DR: This work combines for the first time CNFs with colloidal dispersions of vitrimer nanoparticles (VP) into mechanically coherent nanopaper materials that are ductile, stretchable and offer high water resistance in nanopapers containing cellulose nanofibrils.

TL;DR: This Review summarizes the fabrication methods, characterization techniques and main applications of conductive 3D scaffolds based on conductive polymers, and presents an overview of the emerging strategies developed to manufacture 3D conductive scaffolds, the techniques used to fully characterize them, and the biomedical fields where they have been applied.

TL;DR: The design, synthesis and characterization of self-assembled nanostructures, which integrate on their surface antibacterial peptides, and these nanoassemblies significantly inhibit biofilm formation and eradicate the already formed biofilms of Pseudomonas aeruginosa and Candida albicans.

TL;DR: High strength and significantly water resistance single-cross- linked chitosan-oxidized tannic acid (SC-CS/OTA) composite films and double cross-linked chitOSan/oxidization tannIC acid/FeIII (DC-CS/) composite films were created through a Schiff base reaction and metal coordination to develop biodegradable films.

TL;DR: The compatibility of 18 different amphiphilic polymers for five different hydrophobic drugs was determined empirically and the obtained specificities were compared to theoretical compatibilities derived from either the Flory-Huggins interaction parameters or the Hansen solubility parameters.

TL;DR: The latest advances and associated mechanisms on emerging applications of natural eumelanin in different fields such as functional polymers, energy storage, energy conversion, photocatalysis, photothermal therapy, and wastewater treatment considering its bioinspired properties are discussed.

TL;DR: The results demonstrate that by compatibilization of the CNF- based hydrophilic and the PLA-based hydrophobic components, it is possible to achieve shape control and retention upon 3D printing, opening the possibility of adopting low-solids inks for DIW into dry objects.

TL;DR: A strong in vivo antimicrobial efficacy with a log reduction above 3 in a mouse bacterial sepsis model has been obtained and present a promising prospect for Dex- g-K nF m in biomedical applications.