C
Cheng-Peng Li
Researcher at Chongqing Medical University
Publications - 5
Citations - 193
Cheng-Peng Li is an academic researcher from Chongqing Medical University. The author has contributed to research in topics: Lead acetate & Stem cell. The author has an hindex of 4, co-authored 5 publications receiving 172 citations.
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Journal ArticleDOI
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
Jia-Hong Zhu,Xinyi Mu,Jin Zeng,Chunyan Xu,Jun Liu,Meng-Si Zhang,Cheng-Peng Li,Jie Chen,Tin-yu Li,Yaping Wang +9 more
TL;DR: Evidence is provided that ginsenoside Rg1 can improve cognitive ability, protect NSCs/NPCs and promote neurogenesis by enhancing the antioxidant and anti-inflammatory capacity in the hippocampus.
Journal ArticleDOI
Mitochondria defects are involved in lead-acetate-induced adult hematopoietic stem cell decline.
Jun Liu,Dao-Yong Jia,Shi-Zhong Cai,Cheng-Peng Li,Meng-Si Zhang,Yanyan Zhang,Chonghuai Yan,Yaping Wang +7 more
TL;DR: Results indicate that lead acetate perturbs the hematopoietic balance of adult HSCs, associated with cellular mitochondria defects, increased intracellular ROS generation, and in vivo treatment with the antioxidant vitamin C led to reversion of the CD90(+)CD45(-) compartment functional decline.
Journal ArticleDOI
Alleviation of ginsenoside Rg1 on hematopoietic homeostasis defects caused by lead-acetate.
TL;DR: Ginsenoside Rg1 (Rg1), extracted from the Chinese herb Panax ginseng, remarkably ameliorates the lead acetate-caused hematological index distortion as well as advanced hematopoietic stem cells (HSCs) aging and aging associated inflammation response.
Journal Article
[Research of anti-aging mechanism of ginsenoside Rg1 on brain].
Cheng-Peng Li,Meng-Si Zhang,Jun Liu,Shan Geng,Jing Li,Jia-Hong Zhu,Yanyan Zhang,Yan-yan Jia,Lu Wang,Shun-he Wang,Yaping Wang +10 more
TL;DR: Improve of antioxidant ability, regulating the level of proinflammatory cytokines and regulation of telomerase system may be the underlying anti-aging mechanism of Ginsenoside Rg1.
Journal Article
[Biological mechanisms of human-derived leukemia stem cells senescence regulated by Angelica sinensis polysaccharide].
Dao-Yong Jia,Jun Liu,Cheng-Peng Li,Jing Li,Meng-Si Zhang,Yanyan Zhang,Jing Peng-Wei,Chun-Yan Xu,Yaping Wang +8 more
TL;DR: ASP can induce human leukemia stem cell senescence in vitro, the mechanism involved may be related to ASP regulation P16-Rb signaling pathways.