Cheng-Ting Zi

TL;DR: Investigation of the 95% EtOH extract of stems of Dendrobium findlayanum afforded four new seco-dendrobines, findlayines A-D (1-4) and four new phenolic compounds, dendrofindlaphenols A-C (7, 9, and 10) and 6″-de-O-methyldendro findlaphenol A (8).

TL;DR: Biological evaluation of bibenzyl derivatives against five human cell lines indicated that seven of those compounds exhibited broad-spectrum and cytotoxic activities with IC50 values ranging from 2.2 to 21.2 μM, and those rare bibensyl dimers exhibited cytot toxic activities in vitro and the cytotoxicity decreased as the number of oxygen-containing groups in the structure decreases.

TL;DR: Phytochemical investigation of the n-butanol fraction of this plant led to the isolation of four new 2,6-dideoxyhexose-C-glycosyl flavones, including luteolin that enhanced NGF-induced neurite outgrowth in PC12 cells at 50.0μM.

TL;DR: Two novel EGCG glycosides were chemoselectively synthesized by a chemical modification strategy and appear to be useful, and further studies regarding their biological activity are in progress.

TL;DR: The structures of these new compounds were elucidated by means of extensive spectroscopic analyses, and the absolute configuration of compound 1 was determined by single crystal X-ray diffraction and quantum calculations.