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Chenyuan Huang
Researcher at National University of Singapore
Publications - 12
Citations - 196
Chenyuan Huang is an academic researcher from National University of Singapore. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 6 publications receiving 78 citations.
Papers
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Journal ArticleDOI
Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers.
Suet Yen Chong,Choon Keong Lee,Chenyuan Huang,Yi Hsuan Ou,Christopher J. Charles,Arthur Mark Richards,Yub Raj Neupane,Maria Vazquez Pavon,Olga Zharkova,Giorgia Pastorin,Jiong-Wei Wang +10 more
TL;DR: The recent advances and applications of EV-based biomarkers and therapeutics are reviewed and the potential of EVs as a drug delivery and theranostic platform for CVD will also be discussed.
Journal ArticleDOI
Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies.
Pol Escudé Martinez de Castilla,Lingjun Tong,Chenyuan Huang,Alexandros Marios Sofias,Giorgia Pastorin,Xiaoyuan Chen,Gert Storm,Raymond M. Schiffelers,Jiong-Wei Wang +8 more
TL;DR: In this paper, extracellular vesicles (EVs) have emerged as an attractive drug delivery system and the authors assess their pre-clinical applications, in the form of a systematic review.
Book ChapterDOI
Extracellular vesicles in cardiovascular disease.
Chenyuan Huang,Yub Raj Neupane,Xiong Chang Lim,Rawan Shekhani,Bertrand Czarny,Matthias G. Wacker,Giorgia Pastorin,Jiong-Wei Wang +7 more
TL;DR: An overview of the recent advances in EV-based biomarker discovery is provided, the potential usefulness of EVs and EV mimetics for therapeutic treatment and drug delivery in cardiovascular disease is highlighted and the challenges of current methodologies for isolation, purification and fabrication of EVs are discussed.
Journal ArticleDOI
Lyophilization Preserves the Intrinsic Cardioprotective Activity of Bioinspired Cell-Derived Nanovesicles.
Yub Raj Neupane,Chenyuan Huang,Xiaoyuan Wang,Wei Heng Chng,Gopalakrishnan Venkatesan,Gopalakrishnan Venkatesan,Olga Zharkova,Matthias G. Wacker,Bertrand Czarny,Gerrit Storm,Jiong-Wei Wang,Giorgia Pastorin +11 more
TL;DR: In this paper, a lyophilization approach was proposed to preserve critical characteristics regarding stability (vesicles' size and protein content), structural integrity, and biological activity of CDNs for enabling long-term storage in freeze-dried form.
Journal ArticleDOI
Investigations on Cellular Uptake Mechanisms and Immunogenicity Profile of Novel Bio-Hybrid Nanovesicles
Yi Hsuan Ou,Jer-Hour Liang,Wei Heng Chng,Ram Pravin Kumar Muthuramalingam,Zi Xiu Ng,Choon Keong Lee,Yub Raj Neupane,Jia Ning Nicolette Yau,Sitong Zhang,Charles Kang Liang Lou,Chenyuan Huang,Jiong-Wei Wang,Giorgia Pastorin +12 more
TL;DR: Data confirmed that nCVTs preserved surface cues from their parent U937 cells and can be rationally engineered to incorporate ligands that enhance the selective uptake and delivery toward target cells and tissues.