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Chien-Chang Chen
Researcher at University of Washington
Publications - 1
Citations - 56
Chien-Chang Chen is an academic researcher from University of Washington. The author has contributed to research in topics: Interleukin 33 & Inflammation. The author has an hindex of 1, co-authored 1 publications receiving 26 citations.
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Journal ArticleDOI
Airway epithelium–shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling
Matthew C. Altman,Ying Lai,James D. Nolin,Sydney Long,Chien-Chang Chen,Adrian M. Piliponsky,William A. Altemeier,Megan J. Larmore,Charles W. Frevert,Michael S. Mulligan,Steven F. Ziegler,Jason S. Debley,Jason S. Debley,Michael C. Peters,Teal S. Hallstrand +14 more
TL;DR: Ex vivo modeling of primary airway epithelial cells in organotypic co-culture with mast cells has shown that epithelial-derived IL-33 uniquely induced type-2 cytokines in mast cells, which regulated the expression of epithelial IL33 in a feedforward loop.