J
Jason S. Debley
Researcher at University of Washington
Publications - 71
Citations - 1612
Jason S. Debley is an academic researcher from University of Washington. The author has contributed to research in topics: Medicine & Asthma. The author has an hindex of 21, co-authored 48 publications receiving 1277 citations. Previous affiliations of Jason S. Debley include Seattle Children's & Children's Memorial Hospital.
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Journal ArticleDOI
Thymic stromal lymphopoietin is induced by respiratory syncytial virus–infected airway epithelial cells and promotes a type 2 response to infection
Hai Chon Lee,Mark B. Headley,Mark B. Headley,Yueh Ming Loo,Aaron A. Berlin,Michael Gale,Jason S. Debley,Jason S. Debley,Nicholas W. Lukacs,Steven F. Ziegler,Steven F. Ziegler +10 more
TL;DR: It is suggested that RSV can use an innate antiviral signaling pathway to drive a potentially nonproductive immune response and has important implications for the role of TSLP in viral immune responses in general.
Iconographies supplémentaires de l'article : Airway epithelial cells from asthmatic children differentially express proremodeling factors
Jesus M. Lopez-Guisa,Claire Powers,Daniele File,Elizabeth Cochrane,Nathalia Jimenez,Jason S. Debley +5 more
TL;DR: Nasal epithelial cells might be a suitable surrogate for bronchial cells that could facilitate investigation of the airway epithelium in future longitudinal pediatric studies.
Journal ArticleDOI
Airway epithelial cells from asthmatic children differentially express proremodeling factors
Jesus M. Lopez-Guisa,Claire Powers,Daniele File,Elizabeth Cochrane,Nathalia Jimenez,Jason S. Debley,Jason S. Debley +6 more
TL;DR: In this paper, the airway epithelial cells (AECs) from asthmatic children differentially express TGF-β2, VEGF, ADAM33, and periostin compared with cells from atopic nonasthmatic and healthy children intrinsically or in response to IL-4/IL-13 stimulation.
Journal ArticleDOI
Interplay of extracellular matrix and leukocytes in lung inflammation.
Thomas N. Wight,Charles W. Frevert,Jason S. Debley,Stephen R. Reeves,William C. Parks,Steven F. Ziegler +5 more
TL;DR: Collection of bronchial epithelial cells from asthmatic children co-cultured with human lung fibroblasts generate an ECM that is adherent for monocytes/macrophages makes them attractive candidates for therapeutic intervention.
Journal ArticleDOI
Childhood asthma hospitalization risk after cesarean delivery in former term and premature infants.
TL;DR: Cesarean delivery was associated with subsequent asthma hospitalization only in premature infants, and other factors in addition to the hygiene hypothesis, including genetic and in utero influences associated with maternal asthma, may contribute to the increased risk of asthma in prematurely infants.