C
Christelle Laguillier
Researcher at University of Paris
Publications - 18
Citations - 698
Christelle Laguillier is an academic researcher from University of Paris. The author has contributed to research in topics: Chemokine & Alcoholic liver disease. The author has an hindex of 12, co-authored 16 publications receiving 630 citations. Previous affiliations of Christelle Laguillier include French Institute of Health and Medical Research.
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Journal ArticleDOI
PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis
Erwan Guyot,Angela Sutton,Pierre Rufat,Christelle Laguillier,Abdellah Mansouri,Richard Moreau,Nathalie Ganne-Carrié,Michel Beaugrand,N. Charnaux,Jean-Claude Trinchet,Pierre Nahon +10 more
TL;DR: This study provides key data that affirm the influence of the rs738409 (GG) genotype on the occurrence of HCC in patients with alcoholic cirrhosis and refines the selection of patients at higher risk of liver cancer development.
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RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans
Nadine Suffee,Hanna Hlawaty,Anne Meddahi-Pellé,Loïc Maillard,Liliane Louedec,Oualid Haddad,Loïc Martin,Christelle Laguillier,Benjamin Richard,Olivier Oudar,Didier Letourneur,Nathalie Charnaux,Angela Sutton +12 more
TL;DR: It is demonstrated that chemokine oligomerization and binding to GAGs are essential in RANTES/CCL5-induced angiogenic effects and new therapeutic strategies can be proposed for neo-angiogenesis after vascular injury.
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Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis.
Pierre Nahon,Angela Sutton,Pierre Rufat,Marianne Ziol,Hassan Akouche,Christelle Laguillier,Nathalie Charnaux,Nathalie Ganne-Carrié,Véronique Grando-Lemaire,Gisèle N'Kontchou,Jean-Claude Trinchet,Liliane Gattegno,Dominique Pessayre,Michel Beaugrand +13 more
TL;DR: The combination of the GG‐MPO genotype (leading to high MPO expression) and at least one Ala‐SOD2 allele (associated with high liver iron score) markedly increased the risks of HCC occurrence and death in patients with alcoholic cirrhosis.
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Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells.
Maylis Dagouassat,Nadine Suffee,Hanna Hlawaty,Oualid Haddad,Faten Charni,Christelle Laguillier,Roger Vassy,Loïc Martin,Pierre-Olivier Schischmanoff,Liliane Gattegno,Olivier Oudar,Angela Sutton,Nathalie Charnaux +12 more
TL;DR: The data show that human liver myofibroblasts act on hepatoma cells in a paracrine manner to increase their invasiveness and suggest that my ofibroblast‐derived MCP‐1/CCL2 could be involved in the pathogenesis of hepatocellular carcinoma.
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Latent Membrane Protein 1 Regulates STAT1 through NF-κB-Dependent Interferon Secretion in Epstein-Barr Virus-Immortalized B Cells
Imen Najjar,Fanny Baran-Marszak,Christophe Le Clorennec,Christelle Laguillier,Olivier Schischmanoff,Ibtissam Youlyouz-Marfak,Martin Schlee,Georg W. Bornkamm,Martine Raphael,Jean Feuillard,Remi Fagard +10 more
TL;DR: It is demonstrated that LMP1-induced tyrosine phosphorylation of STAT1 in LCLs is almost exclusively due to the NF-κB-dependent secretion of IFNs.