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Christian Cavelius

Researcher at Leibniz Association

Publications -  36
Citations -  703

Christian Cavelius is an academic researcher from Leibniz Association. The author has contributed to research in topics: Nanoparticle & Particle. The author has an hindex of 16, co-authored 36 publications receiving 625 citations. Previous affiliations of Christian Cavelius include Leibniz Institute for Neurobiology.

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M2 polarization enhances silica nanoparticle uptake by macrophages.

TL;DR: In vivo polarized M2-like primary human tumor-associated macrophage obtained from lung tumors took up more nanoparticles than M1-like alveolar macrophages isolated from the surrounding lung tissue, indicating that the M2 polarization of macrophaging promotes nanoparticle internalization.
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Size-Dependent Localization and Quantitative Evaluation of the Intracellular Migration of Silica Nanoparticles in Caco-2 Cells

TL;DR: The presence and agglomeration inside the cells and the penetration into the nucleus were considered to potentially activate cytotoxic responses and the migration of 32 nm compared to 83 nm particles demonstrated that 32 nm particles obviously migrated faster into and through the cell in the beginning.
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Amplified electrochemical DNA-sensing of nanostructured metal oxide films deposited on disposable graphite electrodes functionalized by chemical vapor deposition

TL;DR: In this paper, an amplified electrochemical sensing method has been presented for the detection of DNA based on the readout resulting from chemical oxidation of guanine on nanoscaled metal oxides (TiO2, SnO2 and Fe3O4) obtained by chemical vapor deposition (CVD) onto pencil graphite electrode (PGE) as electrochemical transducer.
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Superparamagnetic iron oxide nanoparticles impair endothelial integrity and inhibit nitric oxide production.

TL;DR: The data suggest that SPION might substantially alter endothelial integrity and function at therapeutically relevant doses, which are not cytotoxic.
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Crystallization Mechanisms in Convective Particle Assembly

TL;DR: This work uses optical interference microscopy, particle image velocimetry, and particle tracking to analyze particles' trajectory from the liquid reservoir to the film growth front and inside the deposited film as a function of temperature and shows that films assembled by convective mechanisms exhibit greater regularity than those assembled by capillary mechanisms.