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Christian H. Wetzel
Researcher at University of Regensburg
Publications - 90
Citations - 4520
Christian H. Wetzel is an academic researcher from University of Regensburg. The author has contributed to research in topics: Translocator protein & Receptor. The author has an hindex of 29, co-authored 79 publications receiving 3914 citations. Previous affiliations of Christian H. Wetzel include Max Planck Society & Ruhr University Bochum.
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Identification of a testicular odorant receptor mediating human sperm chemotaxis.
Marc Spehr,Günter Gisselmann,Alexandra Poplawski,Jeffrey A. Riffell,Christian H. Wetzel,Richard K. Zimmer,Hanns Hatt +6 more
TL;DR: Results indicate that hOR17-4 functions in human sperm chemotaxis and may be a critical component of the fertilization process, as well as a strong chemoattractant in subsequent behavioral bioassays.
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Progesterone receptor-mediated effects of neuroactive steroids
Rainer Rupprecht,Johannes M. H. M. Reul,Thorsten Trapp,B. van Steensel,Christian H. Wetzel,Klaus Damm,Walter Zieglgänsberger,Florian Holsboer +7 more
TL;DR: The present study shows that these neuroactive steroids can regulate gene expression via the progesterone receptor and regulate neuronal function through their effects on both transmitter-gated ion channels and steroid receptor-regulated gene expression.
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Transient Receptor Potential Channel A1 Is Directly Gated by Calcium Ions
TL;DR: It is demonstrated that, in addition to pungent natural compounds, Ca2+ directly gates heterologously expressed TRPA1 in whole-cell and excised-patch recordings with an apparent EC50 of 905 nm.
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Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus Laevis oocytes.
Christian H. Wetzel,Markus Oles,Christiane Wellerdieck,Michael Kuczkowiak,Günter Gisselmann,Hanns Hatt +5 more
TL;DR: The first evidence for functional expression of a human olfactory receptor protein (OR17–40) is provided and the possibility of now characterizing the sensitivity and specificity of many, if not all, of the hundreds of different human Olfactory receptors is opened.
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Functional expression and characterization of a Drosophila odorant receptor in a heterologous cell system.
Christian H. Wetzel,Hans-Jörg Behrendt,Günter Gisselmann,Klemens F. Störtkuhl,Bernd Hovemann,Hanns Hatt +5 more
TL;DR: This report shows the function and specificity of a member of the recently identified family of Drosophila ORs expressed in a heterologous system using two-electrode voltage-clamp recording.