C
Christiane Volland
Researcher at University of Paris
Publications - 19
Citations - 1618
Christiane Volland is an academic researcher from University of Paris. The author has contributed to research in topics: Permease & Uracil. The author has an hindex of 13, co-authored 19 publications receiving 1588 citations.
Papers
More filters
Journal ArticleDOI
NPI1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase
TL;DR: The results show that the NPI1/Rsp5 ubiquitin‐protein ligase participates in induced degradation of at least two permeases, Gap1p and Fur4p, and probably also other proteins.
Journal ArticleDOI
Ubiquitination Mediated by the Npi1p/Rsp5p Ubiquitin-protein Ligase Is Required for Endocytosis of the Yeast Uracil Permease
TL;DR: The data presented here show that uracil permease also undergoes basal turnover under normal growth conditions, and both basal and stress-stimulated turnover rates were greatly reduced in pep4 mutant cells having defective vacuolar protease activities.
Journal ArticleDOI
Endocytosis and degradation of the yeast uracil permease under adverse conditions.
TL;DR: The degradation of uracil permease in response to several stresses was strikingly slower in the two mutants, end3 and end4, that are deficient in the internalization step of receptor-mediated endocytosis, indicating that internalization is the first step in the permease degradative pathway.
Journal ArticleDOI
Direct sorting of the yeast uracil permease to the endosomal system is controlled by uracil binding and Rsp5p-dependent ubiquitylation
Marie-Odile Blondel,Joëlle Morvan,Sophie Dupré,Danièle Urban-Grimal,Rosine Haguenauer-Tsapis,Christiane Volland +5 more
TL;DR: In this article, the authors show that uracil also triggers the direct routing of its cognate permease from the Golgi apparatus to the endosomal system for degradation, without passage via the plasma membrane.
Journal ArticleDOI
Membrane insertion of uracil permease, a polytopic yeast plasma membrane protein.
TL;DR: In vivo insertion of the hybrid protein bearing the first signal anchor sequence of uracil permease into the endoplasmic reticulum membrane was severely blocked in sec61 and sec62 translocation mutants.