C
Christina Liang
Researcher at Royal North Shore Hospital
Publications - 33
Citations - 962
Christina Liang is an academic researcher from Royal North Shore Hospital. The author has contributed to research in topics: Medicine & Mitochondrial disease. The author has an hindex of 13, co-authored 28 publications receiving 747 citations. Previous affiliations of Christina Liang include Kolling Institute of Medical Research & University of Sydney.
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Journal ArticleDOI
Use of Whole-Exome Sequencing for Diagnosis of Limb-Girdle Muscular Dystrophy: Outcomes and Lessons Learned
Roula Ghaoui,Sandra T. Cooper,Sandra T. Cooper,Monkol Lek,Kristi J. Jones,Kristi J. Jones,Alastair Corbett,Stephen W. Reddel,Merrilee Needham,Christina Liang,Leigh B. Waddell,Leigh B. Waddell,Garth A. Nicholson,Gina L. O'Grady,Gina L. O'Grady,Simranpreet Kaur,Simranpreet Kaur,Royston Ong,Mark R. Davis,Carolyn M. Sue,Nigel G. Laing,Kathryn N. North,Daniel G. MacArthur,Nigel F. Clarke,Nigel F. Clarke +24 more
TL;DR: The central goals were to improve the genetic diagnosis of LGMD, investigate whether the WES platform provides adequate coverage of known LGMD-related genes, and identify new LGMD -related genes.
Journal ArticleDOI
Necrotizing autoimmune myopathy.
Christina Liang,Merrilee Needham +1 more
TL;DR: It is important to recognize and distinguish NAM from other causes of myocyte necrosis, because it has the potential of being amenable to treatment, and may provide a useful diagnostic test in the future, to help differentiate immune from nonimmune statin myopathies.
Journal ArticleDOI
Fibroblast growth factor 21 is a sensitive biomarker of mitochondrial disease
Ryan L. Davis,Christina Liang,Fabienne Edema-Hildebrand,Catherine Riley,Merrilee Needham,Carolyn M. Sue +5 more
TL;DR: This prospective study establishes serum FGF-21 levels as a sensitive biomarker of mitochondrial disease and demonstrates that they are the best predictor of this disorder when compared to serum levels of classical indicators: creatine kinase, lactate, pyruvate, and the lactate to pyruVate ratio.
Journal ArticleDOI
Systematic review of cardiac electrical disease in Kearns–Sayre syndrome and mitochondrial cytopathy
Peter Kabunga,A. Lau,Kevin Phan,Rajesh Puranik,Rajesh Puranik,Christina Liang,Ryan L. Davis,Ryan L. Davis,Carolyn M. Sue,Carolyn M. Sue,Raymond W. Sy,Raymond W. Sy +11 more
TL;DR: The case of a 23year-old female patient with KSS who developed a constellation of cardiac arrhythmias including rapidly progressive conduction system disease and monomorphic ventricular tachycardia with myocardial scarring illustrates the need for cardiologists to be informed about this rare but emerging condition.
Journal ArticleDOI
A comparison of current serum biomarkers as diagnostic indicators of mitochondrial diseases
TL;DR: The data suggest that GDF-15 is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 seems to be more indicative of mitochondrial disease when muscle manifestations are present.