C
Christine Luxemburger
Researcher at Sanofi Pasteur
Publications - 80
Citations - 7590
Christine Luxemburger is an academic researcher from Sanofi Pasteur. The author has contributed to research in topics: Malaria & Mefloquine. The author has an hindex of 45, co-authored 80 publications receiving 7297 citations. Previous affiliations of Christine Luxemburger include Wellcome Trust & John Radcliffe Hospital.
Papers
More filters
Journal ArticleDOI
Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study
François Nosten,François Nosten,M. van Vugt,Ric N. Price,Ric N. Price,Christine Luxemburger,Christine Luxemburger,KL Thway,Alan Brockman,Alan Brockman,Rose McGready,Rose McGready,F O ter Kuile,Sornchai Looareesuwan,Nicholas J. White,Nicholas J. White +15 more
TL;DR: In this area of low malaria transmission, early diagnosis and treatment with combined artesunate and me floquine has reduced the incidence of P. falciparum malaria and halted the progression of mefloquine resistance.
Journal ArticleDOI
Effects of artemisinin derivatives on malaria transmissibility
Ric N. Price,François Nosten,Christine Luxemburger,F O ter Kuile,Lucy Paiphun,Tan Chongsuphajaisiddhi,N J White +6 more
TL;DR: The introduction of the artemisinin derivatives in routine treatment at this study site in mid 1994 was associated with a reduction in the subsequent incidence of falciparum malaria and may prevent the spread of multidrug resistance.
Journal ArticleDOI
Factors contributing to anemia after uncomplicated falciparum malaria
Ric N. Price,Julie A. Simpson,François Nosten,Christine Luxemburger,L Hkirjaroen,F O ter Kuile,Tan Chongsuphajaisiddhi,Nicholas J. White +7 more
TL;DR: Children aged < 5 years of age were more likely than older children or adults to become anemic, and patients coinfected with P. vivax attenuates the anemia of falciparum malaria, presumably by modifying the severity of the infection.
Journal ArticleDOI
The epidemiology of severe malaria in an area of low transmission in Thailand
Christine Luxemburger,Christine Luxemburger,Françoise Ricci,François Nosten,François Nosten,Dominique Raimond,Saw Bathet,Nicholas J. White,Nicholas J. White +8 more
TL;DR: The predisposing factors, clinical presentation, and outcome of severe malaria in a Karen community living on the western border of Thailand were studied over a period of 2 years, suggesting that P. vivax may attenuate the severity of P. falciparum malaria.
Journal ArticleDOI
Adverse effects in patients with acute falciparum malaria treated with artemisinin derivatives.
Ric N. Price,M. van Vugt,L Phaipun,Christine Luxemburger,Julie A. Simpson,Rose McGready,F O ter Kuile,Am Kham,Tan Chongsuphajaisiddhi,Nicholas J. White,François Nosten +10 more
TL;DR: In a prospective study of acute uncomplicated, multidrug-resistant falciparum malaria on the western border of Thailand, the oral artemisinin derivatives were used alone in the treatment of 836 patients (artesunate 630, artemether 206), were combined with mefloquine (15-25 mg base/kg) in 2,826 patients, and me floquine alone was used in 1,303 patients as discussed by the authors.