C
Christoph Eilenberger
Researcher at Vienna University of Technology
Publications - 18
Citations - 350
Christoph Eilenberger is an academic researcher from Vienna University of Technology. The author has contributed to research in topics: Organ-on-a-chip & 3D cell culture. The author has an hindex of 6, co-authored 15 publications receiving 173 citations. Previous affiliations of Christoph Eilenberger include University of Natural Resources and Life Sciences, Vienna.
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Journal ArticleDOI
Acoustic and hybrid 3D-printed electrochemical biosensors for the real-time immunodetection of liver cancer cells (HepG2).
Samar Damiati,Samar Damiati,Seta Küpcü,Martin Peacock,Christoph Eilenberger,Mazin A. Zamzami,Ishtiaq Qadri,Hani Choudhry,Uwe B. Sleytr,Bernhard Schuster +9 more
TL;DR: Both fabricated acoustic and electrochemical sensing platforms can detect cancer cells and therefore may have further potential in other clinical applications and drug-screening studies.
Journal ArticleDOI
Effect of Spheroidal Age on Sorafenib Diffusivity and Toxicity in a 3D HepG2 Spheroid Model.
TL;DR: It is demonstrated thatSpheroidal aging directly influences drug response due to the evolution of spheroid micro-structure and organo-typic functions, that alter inward diffusion, thus drug uptake.
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Characterization of four functional biocompatible pressure-sensitive adhesives for rapid prototyping of cell-based lab-on-a-chip and organ-on-a-chip systems.
Sebastian R.A. Kratz,Christoph Eilenberger,Patrick Schuller,Barbara Bachmann,Sarah Spitz,Peter Ertl,Mario Rothbauer +6 more
TL;DR: Characterization of four functional biomedical-grade pressure sensitive adhesives for rapid prototyping applications including structuring precision, physical and optical properties as well as biocompatibilities shows that both simple and complex microdevices can be designed, fabricated and tested in less than 1 hour.
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Optimized alamarBlue assay protocol for drug dose-response determination of 3D tumor spheroids.
Christoph Eilenberger,Christoph Eilenberger,Sebastian R.A. Kratz,Mario Rothbauer,Eva-Kathrin Ehmoser,Peter Ertl,Seta Küpcü +6 more
TL;DR: In this paper, the authors optimized the standard alamarBlue® proliferation/viability protocol for tumor spheroid cultures to enhance assay precision during toxicological drug screening, which usually suggests an incubation time of 2-4?hours.
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Engineering of three-dimensional pre-vascular networks within fibrin hydrogel constructs by microfluidic control over reciprocal cell signaling
Barbara Bachmann,Sarah Spitz,Mario Rothbauer,Christian Jordan,Michaela Purtscher,Helene Zirath,Patrick Schuller,Christoph Eilenberger,Syed Faheem Ali,Severin Mühleder,Eleni Priglinger,Michael Harasek,Heinz Redl,Wolfgang Holnthoner,Peter Ertl +14 more
TL;DR: Finite volume CFD simulations of different sized molecules vital for pre-vascular network formation into and out of the hydrogel constructs found that interstitial flow enhances growth factor supply to the cells in the bulk of the chamber but elutes cellular secretome, resulting in truncated, premature vascularization.