C
Christoph Hock
Researcher at University of Zurich
Publications - 121
Citations - 9331
Christoph Hock is an academic researcher from University of Zurich. The author has contributed to research in topics: Alzheimer's disease & Single-nucleotide polymorphism. The author has an hindex of 50, co-authored 121 publications receiving 8743 citations. Previous affiliations of Christoph Hock include Karolinska Institutet & University Hospital of Basel.
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Journal ArticleDOI
Antibodies against β-Amyloid Slow Cognitive Decline in Alzheimer's Disease
Christoph Hock,Uwe Konietzko,Johannes Streffer,Jay Tracy,Andri Signorell,Britta Müller-Tillmanns,Ulrike Lemke,Katharina Henke,Eva Moritz,Esmeralda Garcia,M. Axel Wollmer,Daniel Umbricht,Dominique J.-F. de Quervain,Marc Hofmann,Alessia Maddalena,Andreas Papassotiropoulos,Roger M. Nitsch +16 more
TL;DR: It is established that antibodies against beta-amyloid plaques can slow cognitive decline in patients with Alzheimer's disease.
Journal ArticleDOI
Acute cortisone administration impairs retrieval of long-term declarative memory in humans.
Dominique J.-F. de Quervain,Dominique J.-F. de Quervain,Benno Roozendaal,Roger M. Nitsch,James L. McGaugh,Christoph Hock,Christoph Hock +6 more
TL;DR: 1. Hazelrigg, T. H., Bartsch, D. & Kandel, E. R.
Journal ArticleDOI
Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas.
TL;DR: Decreased levels of BDNF may constitute a lack of trophic support and, thus, may contribute to the degeneration of specific neuronal populations in the AD-affected brain, including the basal forebrain cholinergic system.
Journal ArticleDOI
Decrease in parietal cerebral hemoglobin oxygenation during performance of a verbal fluency task in patients with Alzheimer's disease monitored by means of near-infrared spectroscopy (NIRS)--correlation with simultaneous rCBF-PET measurements.
Christoph Hock,Kersten Villringer,Franz Müller-Spahn,Rüdiger Wenzel,Hauke R. Heekeren,Sigrid Schuh-Hofer,Marc Hofmann,Satoshi Minoshima,Markus Schwaiger,Ulrich Dirnagl,Arno Villringer +10 more
TL;DR: In Alzheimer's disease a marked reduction of regional cerebral blood flow and cerebral hemoglobin oxygenation may occur during activation of brain function, probably mainly in degenerating brain areas, such as the parietal cortex.
Journal ArticleDOI
Low-dose cortisol for symptoms of posttraumatic stress disorder.
Amanda Aerni,Rafael Traber,Christoph Hock,Benno Roozendaal,Gustav Schelling,Andreas Papassotiropoulos,Roger M. Nitsch,Ulrich Schnyder,Dominique J.-F. de Quervain +8 more
TL;DR: The results of this pilot study indicate that low-dose cortisol treatment reduces the cardinal symptoms of PTSD.