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Christopher R. Loeffler
Researcher at Food and Drug Administration
Publications - 13
Citations - 353
Christopher R. Loeffler is an academic researcher from Food and Drug Administration. The author has contributed to research in topics: Ciguatoxin & Biology. The author has an hindex of 6, co-authored 8 publications receiving 238 citations.
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Journal ArticleDOI
An Updated Review of Ciguatera Fish Poisoning: Clinical, Epidemiological, Environmental, and Public Health Management.
Melissa A. Friedman,Mercedes Fernandez,Lorraine C. Backer,Robert W. Dickey,Jeffrey N. Bernstein,Kathleen Schrank,Steven R. Kibler,Wendy Stephan,Matthew O. Gribble,Paul K. Bienfang,Robert E. Bowen,Stacey L. DeGrasse,Harold A. Flores Quintana,Christopher R. Loeffler,Richard Weisman,Donna Blythe,Elisa Berdalet,Ram Ayyar,Danielle Clarkson-Townsend,Karen Swajian,Ronald A. Benner,Tom D. Brewer,Lora E. Fleming +22 more
TL;DR: A proposed universal case definition for CFP is provided designed to account for the variability in symptom presentation across different geographic regions and global dimensions, prevention, future directions, and recommendations for clinicians and patients are provided.
Journal ArticleDOI
Prevalence of ciguatoxins in lionfish (Pterois spp.) from Guadeloupe, Saint Martin, and Saint Barthélmy Islands (Caribbean)
Lucía Soliño,Saha Widgy,Anthony Pautonnier,Jean Turquet,Christopher R. Loeffler,Harold A. Flores Quintana,Jorge Diogène +6 more
TL;DR: Information is provided about the potential hazard of ciguatera associated with the consumption of lionfish from known endemic areas and the utility of the cell-based assay combined with LC-MS/MS to assess activity and to provide structural confirmation of CTXs respectively.
Journal ArticleDOI
Ciguatoxin prevalence in 4 commercial fish species along an oceanic exposure gradient in the US Virgin Islands.
Christopher R. Loeffler,Alison Robertson,Harold A. Flores Quintana,Miguel F. Canals Silander,Tyler B. Smith,David A. Olsen +5 more
TL;DR: Investigation of the prevalence of ciguatoxins in 4 commonly marketed and consumed species across an oceanic gradient from the US Virgin Islands concurred with spatial ciguatera fish poisoning prevalence information provided by local fishers in theUS Virgin Islands and demonstrates how partnerships between researchers and fishers can aid the improvement of science-based ciguatoraFish poisoning management.
Journal ArticleDOI
Effects of grazing, nutrients, and depth on the ciguatera-causing dinoflagellate Gambierdiscus in the US Virgin Islands
TL;DR: The significant effect of grazing and disturbance observed in this study suggests that changes in reef herbivore and detritivore feeding selectivity and grazing rates may have large impacts on the areal density of Gambierdiscus in natural systems.
Journal ArticleDOI
Investigation of ciguatoxins in invasive lionfish from the greater caribbean region: Implications for fishery development.
D. Ransom Hardison,William C. Holland,H. Taiana Darius,Mireille Chinain,Patricia A. Tester,Damian Shea,Alex K. Bogdanoff,James A. Morris,Harold A. Flores Quintana,Christopher R. Loeffler,Dayne Buddo,R. Wayne Litaker +11 more
TL;DR: An initial geographic assessment of CTX toxicity in lionfish from the Caribbean and Gulf of Mexico was conducted, finding the highest frequencies of lionfish containing measurable CTX occurred in areas known to be high-risk regions for CFP in the central to eastern Caribbean.