Institution
University of Puerto Rico at Mayagüez
Education•Mayagüez, Puerto Rico, United States•
About: University of Puerto Rico at Mayagüez is a education organization based out in Mayagüez, Puerto Rico, United States. It is known for research contribution in the topics: Large Hadron Collider & Lepton. The organization has 3702 authors who have published 5383 publications receiving 162724 citations. The organization is also known as: UPRM & RUM.
Topics: Large Hadron Collider, Lepton, Standard Model, Higgs boson, Muon
Papers published on a yearly basis
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TL;DR: The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations, and has reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-generation sequencing, deep exome sequencing, and dense microarray genotyping.
Abstract: The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-genome sequencing, deep exome sequencing, and dense microarray genotyping. We characterized a broad spectrum of genetic variation, in total over 88 million variants (84.7 million single nucleotide polymorphisms (SNPs), 3.6 million short insertions/deletions (indels), and 60,000 structural variants), all phased onto high-quality haplotypes. This resource includes >99% of SNP variants with a frequency of >1% for a variety of ancestries. We describe the distribution of genetic variation across the global sample, and discuss the implications for common disease studies.
12,661 citations
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TL;DR: In this paper, results from searches for the standard model Higgs boson in proton-proton collisions at 7 and 8 TeV in the CMS experiment at the LHC, using data samples corresponding to integrated luminosities of up to 5.8 standard deviations.
8,857 citations
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Dartmouth College1, Beth Israel Deaconess Medical Center2, Brigham and Women's Hospital3, Université libre de Bruxelles4, Wake Forest University5, University of Puerto Rico at Mayagüez6, National Institutes of Health7, Science Applications International Corporation8, Massachusetts Institute of Technology9
TL;DR: This article showed that focal segmental glomerulosclerosis (FSGS) and hypertension-attributed end-stage kidney disease (H-ESKD) are associated with two independent sequence variants in the APOL1 gene on chromosome 22.
Abstract: African Americans have higher rates of kidney disease than European Americans. Here, we show that, in African Americans, focal segmental glomerulosclerosis (FSGS) and hypertension-attributed end-stage kidney disease (H-ESKD) are associated with two independent sequence variants in the APOL1 gene on chromosome 22 {FSGS odds ratio = 10.5 [95% confidence interval (CI) 6.0 to 18.4]; H-ESKD odds ratio = 7.3 (95% CI 5.6 to 9.5)}. The two APOL1 variants are common in African chromosomes but absent from European chromosomes, and both reside within haplotypes that harbor signatures of positive selection. ApoL1 (apolipoprotein L-1) is a serum factor that lyses trypanosomes. In vitro assays revealed that only the kidney disease-associated ApoL1 variants lysed Trypanosoma brucei rhodesiense. We speculate that evolution of a critical survival factor in Africa may have contributed to the high rates of renal disease in African Americans.
1,539 citations
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Massachusetts Institute of Technology1, Illinois Institute of Technology2, Franklin W. Olin College of Engineering3, Kent State University4, Rensselaer Polytechnic Institute5, Texas A&M University6, Tokyo Institute of Technology7, Ulsan National Institute of Science and Technology8, University of Naples Federico II9, Sasol10, University of Leeds11, University of Pittsburgh12, Indian Institute of Technology Madras13, Université libre de Bruxelles14, Silesian University of Technology15, North Carolina State University16, ETH Zurich17, IBM18, The Chinese University of Hong Kong19, Stanford University20, University of Puerto Rico at Mayagüez21, South Dakota School of Mines and Technology22, Korea Aerospace University23, Nanyang Technological University24, Helmut Schmidt University25, National Institute of Standards and Technology26, Korea University27, Indian Institute of Technology Kharagpur28, Indira Gandhi Centre for Atomic Research29, Queen Mary University of London30, Argonne National Laboratory31
TL;DR: The International Nanofluid Property Benchmark Exercise (INPBE) as mentioned in this paper was held in 1998, where the thermal conductivity of identical samples of colloidally stable dispersions of nanoparticles or "nanofluids" was measured by over 30 organizations worldwide, using a variety of experimental approaches, including the transient hot wire method, steady state methods, and optical methods.
Abstract: This article reports on the International Nanofluid Property Benchmark Exercise, or INPBE, in which the thermal conductivity of identical samples of colloidally stable dispersions of nanoparticles or “nanofluids,” was measured by over 30 organizations worldwide, using a variety of experimental approaches, including the transient hot wire method, steady-state methods, and optical methods. The nanofluids tested in the exercise were comprised of aqueous and nonaqueous basefluids, metal and metal oxide particles, near-spherical and elongated particles, at low and high particle concentrations. The data analysis reveals that the data from most organizations lie within a relatively narrow band (±10% or less) about the sample average with only few outliers. The thermal conductivity of the nanofluids was found to increase with particle concentration and aspect ratio, as expected from classical theory. There are (small) systematic differences in the absolute values of the nanofluid thermal conductivity among the various experimental approaches; however, such differences tend to disappear when the data are normalized to the measured thermal conductivity of the basefluid. The effective medium theory developed for dispersed particles by Maxwell in 1881 and recently generalized by Nan et al. [J. Appl. Phys. 81, 6692 (1997)], was found to be in good agreement with the experimental data, suggesting that no anomalous enhancement of thermal conductivity was achieved in the nanofluids tested in this exercise.
942 citations
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TL;DR: In this article, the authors summarized data for δ18O in zircons that have been analyzed from 1,200 dated rocks ranging over 96% of the age of Earth.
Abstract: Analysis of δ18O in igneous zircons of known age traces the evolution of intracrustal recycling and crust-mantle interaction through time. This record is especially sensitive because oxygen isotope ratios of igneous rocks are strongly affected by incorporation of supracrustal materials into melts, which commonly have δ18O values higher than in primitive mantle magmas. This study summarizes data for δ18O in zircons that have been analyzed from 1,200 dated rocks ranging over 96% of the age of Earth. Uniformly primitive to mildly evolved magmatic δ18O values are found from the first half of Earth history, but much more varied values are seen for younger magmas. The similarity of values throughout the Archean, and comparison to the composition of the “modern” mantle indicate that δ18O of primitive mantle melts have remained constant (±0.2‰) for the past 4.4 billion years. The range and variability of δ18O in all Archean zircon samples is subdued (δ18O(Zrc)=5–7.5‰) ranging from values in high temperature equilibrium with the mantle (5.3± 0.3‰) to slightly higher, more evolved compositions (6.5–7.5‰) including samples from: the Jack Hills (4.4–3.3 Ga), the Beartooth Mountains (4.0–2.9 Ga), Barberton (3.5–2.7 Ga), the Superior and Slave Provinces (3.0 to 2.7 Ga), and the Lewisian (2.7 Ga). No zircons from the Archean have been analyzed with magmatic δ18O above 7.5‰. The mildly evolved, higher Archean values (6.5–7.5‰) are interpreted to result from exchange of protoliths with surface waters at low temperature followed by melting or contamination to create mildly elevated magmas that host the zircons. During the Proterozoic, the range of δ18O(Zrc) and the highest values gradually increased in a secular change that documents maturation of the crust. After ∼1.5 Ga, high δ18O zircons (8 to >10‰) became common in many Proterozoic and Phanerozoic terranes reflecting δ18O(whole rock) values from 9 to over 12‰. The appearance of high δ18O magmas on Earth reflects nonuniformitarian changes in the composition of sediments, and rate and style of recycling of surface-derived material into magmas within the crust.
940 citations
Authors
Showing all 3715 results
Name | H-index | Papers | Citations |
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David Miller | 203 | 2573 | 204840 |
Alan D. Lopez | 172 | 863 | 259291 |
Bradley Cox | 169 | 2150 | 156200 |
Christopher Hill | 144 | 1562 | 128098 |
Daniela Bortoletto | 143 | 1883 | 108433 |
Christopher George Tully | 142 | 1843 | 111669 |
Robert Hirosky | 139 | 1697 | 106626 |
Peter Elmer | 135 | 1780 | 97836 |
James D. Olsen | 133 | 1513 | 95637 |
Virgil E Barnes | 132 | 1912 | 100156 |
Petra Merkel | 132 | 1496 | 92803 |
Gino Bolla | 132 | 1341 | 88999 |
Ben Bylsma | 132 | 1174 | 88756 |
Daniel Robert Marlow | 131 | 1379 | 88530 |
Sudhir Malik | 130 | 1669 | 98522 |