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Chrong-Reen Wang

Researcher at National Cheng Kung University

Publications -  94
Citations -  3019

Chrong-Reen Wang is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Arthritis & Systemic lupus erythematosus. The author has an hindex of 29, co-authored 80 publications receiving 2690 citations.

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Methotrexate Conjugated to Gold Nanoparticles Inhibits Tumor Growth in a Syngeneic Lung Tumor Model

TL;DR: By combining nanomaterials with anticancer drugs MTX-AuNP may be more effective than free MTX for cancer treatment, according to cytotoxic effect in vitro and antitumor effect in vivo.
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Decreased CD4+CD25+ T Cells in Peripheral Blood of Patients with Systemic Lupus Erythematosus

TL;DR: This is the first study to demonstrate that patients with SLE had decreased CD4+CD25+ T cells, and the exact role of this subset of T cells in the pathogenesis of SLE remains to be elucidated.
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Amelioration of collagen-induced arthritis in rats by Nanogold

TL;DR: The results are the first to demonstrate that intraarticular administration of nanogold ameliorates the clinical course of CIA in rats, and demonstrate proof of principle for the use of Nanogold as a novel therapeutic agent for the treatment of RA.
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Use of HLA-B∗58: 01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: National prospective cohort study

TL;DR: Prospective screening of the HLA-B*58:01 allele, coupled with an alternative drug treatment for carriers, significantly decreased the incidence of allopurinol induced SCARs in Taiwanese medical centres.
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Brief report: amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

TL;DR: This study is the first to demonstrate that lentivirus-mediated silencing of miR-223 can reduce disease severity of experimental arthritis.