E
Esmeralda Valiente
Researcher at University of London
Publications - 24
Citations - 1505
Esmeralda Valiente is an academic researcher from University of London. The author has contributed to research in topics: Vibrio vulnificus & Clostridium difficile. The author has an hindex of 18, co-authored 24 publications receiving 1329 citations. Previous affiliations of Esmeralda Valiente include University of Valencia.
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Journal ArticleDOI
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
Richard A. Stabler,Miao-Xia He,Lisa F. Dawson,Melissa J. Martin,Esmeralda Valiente,Craig Corton,Trevor D. Lawley,Mohammed Sebaihia,Michael A. Quail,Graham Rose,Dale N. Gerding,Maryse Gibert,Michel R. Popoff,Julian Parkhill,Gordon Dougan,Brendan W. Wren +15 more
TL;DR: This study provides genetic markers for the identification of 027 strains and offers a unique opportunity to explain the recent emergence of a hypervirulent bacterium.
Journal ArticleDOI
Characterisation of Clostridium difficile biofilm formation, a role for Spo0A.
Lisa F. Dawson,Esmeralda Valiente,Alexandra Faulds-Pain,Elizabeth H. Donahue,Brendan W. Wren +4 more
TL;DR: It is demonstrated that C. difficile aggregates and forms biofilms in vitro on abiotic surfaces by an extracellular polymeric substance (EPS), which may have significant implications for infection, treatment and relapse.
Journal ArticleDOI
Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations.
Richard A. Stabler,Lisa F. Dawson,Esmeralda Valiente,M. D. Cairns,M. D. Cairns,M. D. Cairns,Melissa J. Martin,Elizabeth H. Donahue,Thomas V. Riley,J. Glenn Songer,Ed J. Kuijper,Kate E. Dingle,Brendan W. Wren +12 more
TL;DR: The evolutionary origin of dominant C. difficile lineages is defined and it is demonstrated that C. Difficile is continuing to evolve in concert with human activity.
Journal ArticleDOI
Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage
TL;DR: It is concluded that there should be a heightened awareness of newly identified PCR ribotypes such as 176, 198 and 244, and that they may be as problematic as the notorious 027 strains.
Journal ArticleDOI
The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move
TL;DR: The emergence, population structure, dissemination and evolution of this lineage, which has been associated with increases in the incidence and severity of disease and mortality, is reviewed.