Chwan-Deng Hsiao

TL;DR: Sequence comparisons of the class 3 ALDH with other ALDHs indicate a similar polypeptide fold, novel NAD-binding mode and catalytic site for this family, and a mechanism for enzymatic specificity and activity is postulated.

TL;DR: It is shown that, at least in this case, it is possible to predict one conformational state of a periplasmic binding protein from another conformationalstate of the protein.

TL;DR: The first crystal structure of the pituitary hormone oxytocin complexed with its carrier protein neurophysin has been determined and refined to 3.0 Å resolution and it is found that while the structure is in agreement with the previous crystallographic findings, it differs from the NMR result with regard to how Tyr 2 of the hormone is recognized by Neurophysin.

TL;DR: An analysis of the intensity data using an Requiv plot indicates that the crystal system is orthorhombic, space group P2( 1)2(1)2 (1) 2(1), which is in line with known crystal types of glutamine-binding protein.

TL;DR: Crystals of a cardiotoxin from Taiwan cobra venom have been obtained by the vapor diffusion method using methyl pentanediol as precipitant and the solvent content is estimated to be 53%.