C
Clara Uriel
Researcher at Spanish National Research Council
Publications - 76
Citations - 901
Clara Uriel is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Glycosyl & BODIPY. The author has an hindex of 16, co-authored 71 publications receiving 796 citations. Previous affiliations of Clara Uriel include Durham University.
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Recent Developments in the Ferrier Rearrangement
TL;DR: A review of recent developments in the use of promoters for the Ferrier rearrangement of O-, N-, C- and S-nucleophiles with glycals can be found in this paper.
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Reciprocal Donor Acceptor Selectivity (RDAS) and Paulsen’s Concept of “Match” in Saccharide Coupling
TL;DR: The role of O2 protecting groups in stereocontrol of coupling reactions was formulated 60 years ago and evidence is presented in this article which shows that protecting groups also exercise regioc-control.
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Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity CRYSTAL STRUCTURE OF ACIDIC FIBROBLAST GROWTH FACTOR IN COMPLEX WITH 5-AMINO-2-NAPHTHALENESULFONATE
Carlos Fernández-Tornero,Rosa M. Lozano,Mariano Redondo-Horcajo,Ana M. Gómez,José C. López,Ernesto Quesada,Clara Uriel,Serafin Valverde,Pedro Cuevas,Antonio A. Romero,Guillermo Giménez-Gallego +10 more
TL;DR: The three-dimensional structure of acidic fibroblast growth factor complexed to 5-amino-2-naphthalenesulfonate, the most pharmacologically promising of the identified inhibitors, is solved.
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Unexpected role of O-2 "protecting" groups of glycosyl donors in mediating regioselective glycosidation.
Bert Fraser-Reid,J. Cristobal Lopez,Kokkuvayil Vasu Radhakrishnan,Mateusz Mach,Urs Schlueter,and Ana M. Gomez,Clara Uriel +6 more
TL;DR: Glycosidation of several vicinal diols reveals that exquisite regioselectivity can be achieved by using 2-O-benzoyl n-pentenyl glycoside donors and/or their cyclic 1,2-ortho ester counterparts.
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Iterative, orthogonal strategy for oligosaccharide synthesis based on the regioselective glycosylation of polyol acceptors with partially unprotected n-pentenyl-orthoesters: further evidence for reciprocal donor acceptor selectivity (RDAS)
TL;DR: An efficient iterative, orthogonal protocol based on the regioselective glycosyl coupling of D-mannose polyols with, partially unprotected, n-pentenyl orthoester donors permits the synthesis of linear and branched oligosaccharides with minimal protecting group tampering.