C
Claude Guérin
Researcher at University of Lyon
Publications - 423
Citations - 20188
Claude Guérin is an academic researcher from University of Lyon. The author has contributed to research in topics: ARDS & Mechanical ventilation. The author has an hindex of 54, co-authored 390 publications receiving 16326 citations. Previous affiliations of Claude Guérin include Claude Bernard University Lyon 1 & National Yang-Ming University.
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Journal ArticleDOI
Prone Positioning in Severe Acute Respiratory Distress Syndrome
Claude Guérin,Jean Reignier,Jean-Christophe Richard,Pascal Beuret,Arnaud Gacouin,Thierry Boulain,Emmanuelle Mercier,Michel Badet,Alain Mercat,Olivier Baudin,Marc Clavel,Delphine Chatellier,Samir Jaber,Sylvène Rosselli,Jordi Mancebo,Michel Sirodot,Gilles Hilbert,Christian Bengler,Jack Richecoeur,Marc Gainnier,Frédérique Bayle,Gael Bourdin,Véronique Leray,Raphaële Girard,Loredana Baboi,Louis Ayzac +25 more
TL;DR: In patients with severe ARDS, early application of prolonged prone-positioning sessions significantly decreased 28-day and 90-day mortality.
Journal ArticleDOI
Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome
Laurent Papazian,Jean-Marie Forel,Arnaud Gacouin,Christine Penot-Ragon,Gilles Perrin,Anderson Loundou,Samir Jaber,Jean-Michel Arnal,Didier Perez,Jean-Marie Seghboyan,Jean-Michel Constantin,Pierre Courant,Jean-Yves Lefrant,Claude Guérin,Gwenaël Prat,Sophie Morange,Antoine Roch +16 more
TL;DR: In patients with severe ARDS, early administration of a neuromuscular blocking agent improved the adjusted 90-day survival and increased the time off the ventilator without increasing muscle weakness.
Journal ArticleDOI
High versus Low Blood-Pressure Target in Patients with Septic Shock
Pierre Asfar,Ferhat Meziani,Jean-François Hamel,Fabien Grelon,Bruno Mégarbane,Nadia Anguel,Jean-Paul Mira,Pierre-François Dequin,Soizic Gergaud,Nicolas Weiss,François Legay,Marie Conrad,René Robert,Frédéric Gonzalez,Christophe Guitton,Fabienne Tamion,Jean-Marie Tonnelier,Pierre Guezennec,Thierry Van Der Linden,Antoine Vieillard-Baron,Eric Mariotte,Gael Pradel,Olivier Lesieur,Jean-Damien Ricard,Fabien Hervé,Claude Guérin,Alain Mercat,Jean-Louis Teboul,Peter Radermacher,Abstr Act +29 more
TL;DR: Targeting a mean arterial pressure of 80 to 85 mm Hg, as compared with 65 to 70 mm HG, in patients with septic shock undergoing resuscitation did not result in significant differences in mortality at either 28 or 90 days.
Journal ArticleDOI
Effects of Systematic Prone Positioning in Hypoxemic Acute Respiratory Failure: A Randomized Controlled Trial
Claude Guérin,Sandrine Gaillard,Stéphane Lemasson,Louis Ayzac,Raphaële Girard,Pascal Beuret,Bruno Palmier,Quoc Viet Le,Michel Sirodot,Sylvaine Rosselli,Vincent Cadiergue,Jean-Marie Sainty,Philippe Barbe,Emmanuel Combourieu,Daniel Debatty,Jean Rouffineau,Eric Ezingeard,Olivier Millet,Dominique Guelon,Luc Rodriguez,Olivier Martin,Anne Renault,Jean-Paul Sibille,Michel Kaidomar +23 more
TL;DR: In this paper, the authors showed that placing patients with acute lung injury in the prone position did not increase survival; however, whether those results hold true for patients with hypoxemic acute respiratory failure (ARF) is unclear.
Journal ArticleDOI
Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis.
Sachin Sud,Jan O. Friedrich,Jan O. Friedrich,Paolo Taccone,Federico Polli,Neill K. J. Adhikari,Neill K. J. Adhikari,Roberto Latini,Antonio Pesenti,Claude Guérin,Jordi Mancebo,Martha A. Q. Curley,Rafael Fernandez,Ming Cheng Chan,Pascal Beuret,Gregor Voggenreiter,Maneesh Sud,Gianni Tognoni,Luciano Gattinoni +18 more
TL;DR: Prone ventilation reduces mortality in patients with severe hypoxemia and should not be routine in all patients with AHRF, but may be considered for severely hypoxemic patients.