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Claudia J. Lammel
Researcher at University of California, San Francisco
Publications - 23
Citations - 3044
Claudia J. Lammel is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Neisseria gonorrhoeae & Chlamydia trachomatis. The author has an hindex of 15, co-authored 23 publications receiving 2973 citations. Previous affiliations of Claudia J. Lammel include University of California, Berkeley.
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Journal ArticleDOI
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
Richard S. Stephens,Sue Kalman,Claudia J. Lammel,Jun Fan,Rekha Marathe,L. Aravind,Wayne Mitchell,Lynn Olinger,Roman L. Tatusov,Qixun Zhao,Eugene V. Koonin,Ronald W. Davis +11 more
TL;DR: The phylogenetic mosaic of chlamydial genes, including a large number of genes with phylogenetic origins from eukaryotes, implies a complex evolution for adaptation to obligate intracellular parasitism.
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Comparative genomes of Chlamydia pneumoniae and C. trachomatis.
Sue Kalman,Wayne Mitchell,Wayne Mitchell,Rekha Marathe,Claudia J. Lammel,Jun Fan,Richard W. Hyman,Lynn Olinger,Lynn Olinger,Jane Grimwood,Ronald W. Davis,Richard S. Stephens,Richard S. Stephens +12 more
TL;DR: Analysis of the C. pneumoniae genome revealed 214 protein-coding sequences not found in C. trachomatis, most without homologues to other known sequences, which will provide an understanding of the common biological processes required for infection and survival in mammalian cells.
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Modification by Sialic Acid of Neisseria gonorrhoeae Lipooligosaccharide Epitope Expression in Human Urethral Exudates: An Immunoelectron Microscopic Analysis
Michael A. Apicella,R E Mandrell,M Shero,M E Wilson,J M Griffiss,Geo. F. Brooks,Claudia J. Lammel,J F Breen,Peter A. Rice +8 more
TL;DR: These studies indicate that in vivo modification by sialylation of gonococcal LOS Gal beta 1-4-GlcNAc residue occurs during human infection.
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Neisseria gonorrhoeae Coordinately Uses Pili and Opa To Activate HEC-1-B Cell Microvilli, Which Causes Engulfment of the Gonococci
TL;DR: It is shown that gonococci must express both pili and Opa to be engulfed efficiently by HEC-1-B cells, and also that microvilli must actively participate in the engulfment of the microcolonies.
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Antibody-antigen specificity in the immune response to infection with Neisseria gonorrhoeae.
Claudia J. Lammel,Richard L. Sweet,Peter A. Rice,Joan S. Knapp,Gary K. Schoolnik,David C. Heilbron,Geo. F. Brooks +6 more
TL;DR: Sera and vaginal fluids were tested against gonococcal isolates from the same patients to examine homologous antibody-antigen interactions by use of the western blot technique and found IgG in serum and vaginal fluid reacted with more antigens than did IgA in the same specimens.